Tocriscreen FDA-Approved Drugs Library

Name: Tocriscreen FDA-Approved Drugs Library
Brand: Tocris Bioscience
SKU: 7200

Catalog # 7200

Citations (3)

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Key Product Details

Description:

Drug repurposing library; a library of 190 compounds equivalent to active components of drug formulations approved by the FDA (100 μL 10 mM DMSO solutions)

Key Format Details:

All compounds are equivalent to active components of FDA-approved drug formulations
Full chemical and biological data available in Excell and SD file formats
96-well racks with Matrix storage tubes & SepraSeal caps

Compounds arranged with a maximum of 80 per rack with 3 racks per library
Pre-dissolved in 100 μL 10 mM DMSO solutions
Compounds produced to same high chemical standard as Tocris catalog

Target Classes Covered by the Tocriscreen FDA-approved Drugs Library

The Tocriscreen FDA-approved Drugs Library contains bioactive compounds covering a diverse range of therapeutic classifications, derived using the WHO Anatomical Therapeutic Chemical Classification System code (ATC code).

View Full Technical Details for Tocriscreen FDA-Approved Drugs Library

Product Description

Tocriscreen FDA-Approved Drugs Library is a library of 190 compounds equivalent to the pharmacologically active components of drug formulations approved by the FDA. Compounds supplied pre-dissolved in DMSO (100 μL, 10 mM solution). Contains compounds covering a diverse range of pharmaceutical targets and therapeutic areas e.g. immunology, oncology. Includes both established therapeutics, e.g. tamoxifen (Cat. No. 0999) & paclitaxel (Cat. No. 1097), as well as more recently approved drugs such as darunavir (Cat. No. 6710) & sorafenib (Cat. No. 6814). Ideal for in vitro and in vivo drug repurposing/repositioning studies.

This library replaces the Tocriscreen Library of FDA-Approved Compounds (Cat. No. 5932).

All Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

For more information about this compound library, please download our informative flyer.

Request Compound List

A list of the compounds available in the Tocriscreen FDA-Approved Drugs Library can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.

Technical Data

Storage	Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References

References are publications that support the biological activity of the product.

Li Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 2015 PMID: 26253201
Edwards The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 2014 PMID: 24409953

Citations for Tocriscreen FDA-Approved Drugs Library (3)

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Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen FDA-Approved Drugs Library include:

Edmister et al. (2022) Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles. Sci.Rep.. 12:6120
PMID: 35449173
Mehyar et al. (2020) Using in silico modelling and FRET-based assays in the discovery of novel FDA-approved drugs as inhibitors of MERS-CoV helicase. SAR QSAR Environ Res. 6:1
PMID: 33401979
Shin et al. (2018) Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In Vitro. Viruses. 10:E283
PMID: 29795047

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