Minoxidil
Tocris Bioscience, part of Bio-Techne | Catalog # 0583
Kir6 channel (KATP) opener
Key Product Details
Description
Kir6 channel (KATP) opener
Product Description
Minoxidil is an antihypertensive. Antialopecia agent. Kir6 channel (KATP) activator.Product Specifications
Molecular Weight
209.25
Formula
C9H15N5O
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
CAS Number
38304-91-5
PubChem ID
4201
InChI Key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
SMILES
NC1=CC(=NC(N)=[N+]1[O-])N1CCCCC1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 5.23 | 25 with gentle warming | |
| Ethanol | 5.23 | 25 |
Preparing Stock Solutions
for Minoxidil
The following data is based on the product molecular weight 209.25
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 19.12 mL | 95.58 mL | 191.16 mL |
| 1.25 mM | 3.82 mL | 19.12 mL | 38.23 mL |
| 2.5 mM | 1.91 mL | 9.56 mL | 19.12 mL |
| 12.5 mM | 0.38 mL | 1.91 mL | 3.82 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Meisheri Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil. Biochem.Pharmacol. 1993 PMID: 8435087
- Tsoporis Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats. J.Hypertens. 1993 PMID: 8133016
- Lachgar Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br.J.Dermatol. 1998 PMID: 9580790
Product Specific Notices for Minoxidil
For research use only
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