Minoxidil

Name: Minoxidil
Brand: Tocris Bioscience
SKU: 0583
Rating: 5 (1 reviews)

Catalog # 0583

Citations (1)

(1)

COA / SDS

Order Information

Bio-Techne Corporation

tel: (800) 343-7475 (free phone)

tel: (612) 379-2956

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

View Distributors

Key Product Details

Description:	K_ir6 channel (K_ATP) opener
Chemical Name:	6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
Purity:	≥99% (HPLC)
Molecular Weight:	209.25

View Full Technical Details for Minoxidil

Biological Activity

Minoxidil is an antihypertensive. Antialopecia agent. K_ir6 channel (K_ATP) activator.

Compound Libraries

Minoxidil is also offered as part of the Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt	209.25
Formula	C₉H₁₅N₅O
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	38304-91-5
PubChem ID	4201
InChi Key	ZIMGGGWCDYVHOY-UHFFFAOYSA-N
Smiles	NC1=CC(=NC(N)=[N+]1[O-])N1CCCCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	5.23	25
	DMSO	5.23	25 with gentle warming

Preparing Stock Solutions

The following data is based on the product molecular weight 209.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	19.12 mL	95.58 mL	191.16 mL
1.25 mM	3.82 mL	19.12 mL	38.23 mL
2.5 mM	1.91 mL	9.56 mL	19.12 mL
12.5 mM	0.38 mL	1.91 mL	3.82 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References

References are publications that support the biological activity of the product.

Lachgar Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br.J.Dermatol. 1998 PMID: 9580790
Meisheri Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil. Biochem.Pharmacol. 1993 PMID: 8435087
Tsoporis Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats. J.Hypertens. 1993 PMID: 8133016

Citations for Minoxidil (1)

Showing 1 - 1 of 1 citation Showing All

View all citations for the Small Molecules and Peptides platform.

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for Minoxidil include:

Sun et al. (2014) Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel. Sci Rep. 4:4934
PMID: 24816792

There are no citations that match your criteria.

Showing 1 - 1 of 1 citation Showing All

Customer Reviews (1)

5 out of 5

1 customer rating

5 stars

100%

4 stars

3 stars

2 stars

1 star

Customer Images

Showing 1 - 1 of 1 review Showing All

Filter By:

Minoxidil used to study BK channel opening

Name: Sadequl Islam

Species: Human

Assay Type: In Vitro

Minoxidil was used based on its history as a potent potassium channel opener. It was used to study BK channel opening.

There are no reviews that match your criteria.