Repaglinide

Tocris Bioscience, part of Bio-Techne | Catalog # 3805

Kir6 (KATP) channel blocker
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Key Product Details

Description

Kir6 (KATP) channel blocker

Alternative Names

AG-EE 623ZW

View all Inward Rectifier Potassium Channel Blockers »

Product Description

Repaglinide is a Kir6 (KATP) channel blocker that binds with high affinity for SUR1 when co-expressed with Kir6.2 (Kd = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo.

Product Specifications

Molecular Weight

452.59

Formula

C27H36N2O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid

CAS Number

135062-02-1

PubChem ID

65981

InChI Key

FAEKWTJYAYMJKF-QHCPKHFHSA-N

SMILES

O=C(CC3=CC(OCC)=C(C(O)=O)C=C3)N[C@@H](CC(C)C)C1=CC=CC=C1N2CCCCC2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 45.26 100
Ethanol 45.26 100

Preparing Stock Solutions for Repaglinide

The following data is based on the product molecular weight 452.59

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.21 mL 11.05 mL 22.10 mL
5 mM 0.44 mL 2.21 mL 4.42 mL
10 mM 0.22 mL 1.10 mL 2.21 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Repaglinide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Repaglinide

For research use only

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