Order Information
Shipping Information
$35 to United States
Products in stock will be shipped in 1-3 business days unless specified.
View Distributors
Key Product Details
| Description: | Kir6 (KATP) channel blocker |
| Alternative Names: | Glyburide |
| Chemical Name: | 5-Chloro-N-[2-[4-[[[(Cylcohexylamino)carbonyl]amino]sulphonyl]phenyl]ethyl]-2-methoxybenzamide |
| Purity: | ≥99% (HPLC) |
Complete Your Research
Showing 1-5 of 15 citations
Citations (15)
Citations are publications that use Bio-techne products. Selected citations for Glibenclamide include:
-
O'Malley et al.
(2020)
TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations
J Neurosci.
40:4813
PMID: 32414784 -
Mehmood et al.
(2015)
Antidiarrhoeal, antisecretory and antispasmodic activities of Matricaria chamomilla are mediated predominantly through K(+)-channels activation.
Neuroscience.
15:75
PMID: 25886126 -
Fransen et al.
(2015)
Dissecting out the complex Ca2+-mediated phenylephrine-induced contractions of mouse aortic segments.
Biomed Res Int.
10:e0121634
PMID: 25803863 -
Jiang and Zsombok
(2014)
Regulation of neurons in the dorsal motor nucleus of the vagus by SIRT1.
Front Neurosci.
7:270
PMID: 24454277 -
Chen et al.
(2014)
Characterization of imidazoline receptors in blood vessels for the development of antihypertensive agents.
J Pharmacol Exp Ther.
2014:182846
PMID: 24800210 -
Seto et al.
(2013)
Acute SimV. inhibits K ATP channels of porcine coronary artery myocytes.
J Neurophysiol.
8:e66404
PMID: 23799098 -
Xu
(2012)
Effect of the ginsenoside Rb1 on the spontaneous contraction of intestinal smooth muscle in mice.
World J Gastroenterol.
18:5462
PMID: 23082064 -
Quock et al.
(2011)
The acute antinociceptive effect of HBO2 is mediated by a NO-cyclic GMP-PKG-KATP channel pathway in mice.
Brain Res.
1368:102
PMID: 20977894 -
Saloman et al.
(2011)
Activation of peripheral δ-opioid receptors leads to anti-hyperalgesic responses in the masseter muscle of male and female rats.
PLoS One.
190:379
PMID: 21664434 -
Chung et al.
(2011)
Expression and functional properties of TRPM2 channels in DArgic neurons of the substantia nigra of the rat.
J Korean Med Sci.
106:2865
PMID: 21900507 -
Lee et al.
(2011)
Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension.
Circulation.
124:1160
PMID: 21844078 -
He et al.
(2010)
Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.
J Immunol.
184:5743
PMID: 20393140 -
Song et al.
(2010)
Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts.
PLoS One.
25:380
PMID: 20191036 -
Parsons
(2010)
ATP-sensitive potassium channel-mediated lactate effect on orexin neurons: implications for brain energetics during arousal.
J Neurosci.
30:8061
PMID: 20554857 -
Price et al.
(2008)
Nesfatin-1 inhibits NPY neurons in the arcuate nucleus.
Brain Res.
1230:99
PMID: 18625211
There are no citations that match your criteria.
Customer Reviews
5 out of 5
2 customer ratings
Showing 1-2 of 2 reviews
Filter By:
-
Glibenclamide prolongs action potential duration in LPS-treated cardiomyocytes
Species: OtherAssay Type: In VitroCell Line/Tissue: Ventricular cardiomyocytesPrimary guinea pig ventricular cardiomyocytes were incubated with LPS for 6-10 h. Cells were patched and stimulated at a 1 Hz frequency. Action potentials were recorded before and after glibenclamide (5 microM) containing normal tyrode solution. Glibenclamide prolonged action potential duration in LPS-treated cardiomyocytes; indicating role of KATP channels.
-
Glibenclamide was used to study combination drug effect with B blockers
Species: MouseAssay Type: In VivoGlibenclamide was used in our lab to study combination drug effect. Beta blocker and glibenclamide was administered in combination and separately to study their pattern of action over blood glucose level.
There are no reviews that match your criteria.
