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IL-4 Products

IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R alpha and the common gamma chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R alpha and IL-13 R alpha 1. The type II receptor also transduces IL-13 mediated signals. 

111 results for "IL-4" in Products

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IL-4 Products

IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R alpha and the common gamma chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R alpha and IL-13 R alpha 1. The type II receptor also transduces IL-13 mediated signals. 

111 results for "IL-4" in Products

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

A New rh IL-4 is Now Available! The new protein is mammalian cell expressed!

Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

ELISA

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

BA

Supplied as ready-to-use 5 ug protein balls

Simple Plex Cartridge Kit for quantitation of IL-4. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

Product in process of being discontinued and replaced by a new, improved panel

Product in process of being discontinued and replaced by a new, improved panel

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