8 results for "Glycosylase Inhibitors Small Molecules and Peptides" in Products
Glycosylase Inhibitors: Small Molecules and Peptides
Glycosylases are a group of enzymes that includes glucosidases, mannosidases and heparanases. There are two glucosidase subtypes, α- and β-glucosidase (EC numbers 3.2.1.20 and 3.2.1.21 respectively), which are both found in the gut. They hydrolyze terminal (1,4)α-glucosidic linkages and (1,6)β-glucosidic linkages, liberating α-glucose and β-glucose respectively.
Mannosidases are divided into two subtypes: I and II, (EC numbers 3.2.1.113 and 3.2.1.114 respectively) ...
Potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor
| Chemical Name: | 3,4-Dichlorobenzo[b]thiophene-2-carbohydrazide |
| Purity: | ≥98% (HPLC) |
Inhibitor of class I α-mannosidases
| Chemical Name: | (5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione |
α-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity
| Alternate Names: | N-Butyldeoxynojirimycin hydrochloride,NB-DNJ |
| Chemical Name: | (2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol hydrochloride |
Glucosidase α inhibitor (intestinal)
| Alternate Names: | Bay-g 5421 |
| Chemical Name: | O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glucose |
Inhibitor of α-mannosidase II
| Chemical Name: | (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol |
Irreversible glucocerebrosidase (β-glucosidase) inhibitor; used to generate Gaucher disease models
| Chemical Name: | DL-1,2-Anhydro-myo-inositol |
Glucosidase inhibitor
| Alternate Names: | NN-DNJ |
| Chemical Name: | (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol |
Antiangiogenic. Heparanase inhibitor
| Chemical Name: | 2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid |
| Purity: | ≥97% (HPLC) |
