CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
951 results for "CTLA-4" in Products
951 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6864R |
| Applications: | IHC, mIF, COMET |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6864R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
| Applications: | IHC |
![CTLA-4 Antibody (CTLA4/6868R) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-20735cl1_rabbit-ctla-4-mab-ctla4-6868r-corafluor-1-12920251445917.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6864R |
| Applications: | IHC |
![CTLA-4 Antibody (CTLA4/6864R) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-20818cl1_rabbit-ctla-4-mab-ctla4-6864r-corafluor-1-12920251439712.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #anti-CTLA4 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #anti-CTLA4 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #anti-CTLA4 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
| Applications: | IHC |
![CTLA-4 Antibody (CTLA4/6867R) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-20819cl1_rabbit-ctla-4-mab-ctla4-6867r-corafluor-1-12920251447206.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
| Applications: | IHC |
![CTLA-4 Antibody (rCTLA4/7219) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-20809cl1_mouse-ctla-4-mab-rctla4-7219-corafluor-1-810202510495217.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6864R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #anti-CTLA4 |
| Applications: | ELISA, Flow, Func |