Skip to main content

CTLA-4 Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

70 results for "CTLA-4" in Products

Back to Search Results
Apply

CTLA-4 Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

70 results for "CTLA-4" in Products

Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies

New rh CTLA-4 Available! Increased activity; Enhanced purity; Lower endotoxin specification; CHO expressed!

BA

Biotinylated

ELISA
WB, Flow, CyTOF-ready, Neut
Flow, CyTOF-ready

Recombinant Monoclonal Antibody For Research Use Only

Catalog #: FAB434R
Flow
WB, AgAct
BA
WB

Simple Plex Cartridge Kit for quantitation of CTLA-4. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

Catalog #: BAF476
WB
WB
WB, Flow, CyTOF-ready, ICC
Catalog #: FAB434N
Flow
WB
Catalog #: FAB3252G
Flow

Recombinant Monoclonal Antibody

Flow, ICC

Recombinant Monoclonal Antibody.

Block
Catalog #: FAB9928G
Flow

Recombinant Monoclonal Antibody For Research Use Only

/ 3
Results Per Page
5 10 25 50