Skip to main content

CTLA-4 Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

71 results for "CTLA-4" in Products

Back to Search Results
Apply

Search

Compatible Instrument 

CTLA-4 Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

71 results for "CTLA-4" in Products

WB, Flow, CyTOF-ready, ICC

Simple Plex Human CTLA-4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

ELISA
BA

Biotinylated

WB
ELISA
Flow, CyTOF-ready

Recombinant Monoclonal Antibody For Research Use Only

WB
Flow, CyTOF-ready, ICC

Recombinant Monoclonal Antibody.

Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies

Catalog #: FAB3252N
Flow

Recombinant Monoclonal Antibody

WB, Flow, CyTOF-ready, Neut
BA
BA
Flow

Recombinant Monoclonal Antibody For Research Use Only

ICFlow
Flow, ICC

Recombinant Monoclonal Antibody.

WB, AgAct
Results Per Page
5 10 25 50
/ 3