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CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
71 results for "CTLA-4" in Products
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CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
71 results for "CTLA-4" in Products
| Source : | Sf 21 (baculovirus) |
| Accession # : | Q6GR94 |
| Applications : | Bioactivity |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Source : | CHO |
| Accession # : | P16410 |
| Applications : | Bioactivity |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
Simple Plex Human CTLA-4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Sensitivity : | 0.13 pg/mL |
| Assay Range : | 0.781 - 50 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | Q6GTR6 |
| Applications : | Bioactivity |
Biotinylated
| Source : | HEK293 |
| Accession # : | P16410.3 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #48815 |
| Applications : | Western Blot |
| Assay Range : | 31.3 - 2,000 pg/mL |
| Applications : | ELISA |
Recombinant Monoclonal Antibody For Research Use Only
| Clonality : | Monoclonal |
| Host : | Human IgG1 Clone #Hu111 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Capture, Western Blot |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188B |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188A |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #63828 |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Western Blot |
| Source : | HEK293 |
| Accession # : | XP_005574071 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | NP_001003106.1 |
| Applications : | Bioactivity |
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
| Clonality : | Monoclonal |
| Host : | Human IgG1 Clone #Hu111 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #922101 |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188A |
| Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1003705 |
| Applications : | Functional Assay, Western Blot |
