CTLA-4: Antibodies
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
52 results for "CTLA-4 Primary Antibodies" in Products
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CTLA-4: Antibodies
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
52 results for "CTLA-4 Primary Antibodies" in Products
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #48815 |
Applications : | Western Blot |
Recombinant Monoclonal Antibody For Research Use Only
Clonality : | Monoclonal |
Host : | Human IgG1 Clone #Hu111 |
Applications : | CyTOF-ready, Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Capture, Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2188B |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Recombinant Monoclonal Antibody
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2188A |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #63828 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
Clonality : | Monoclonal |
Host : | Human IgG1 Clone #Hu111 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #922101 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2188A |
Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1003705 |
Applications : | Functional Assay, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Recombinant Monoclonal Antibody
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2188A |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2188B |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
Clonality : | Monoclonal |
Host : | Human IgG1 Clone #Hu111 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2188A |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
Clonality : | Monoclonal |
Host : | Human IgG1 Clone #Hu111 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
Clonality : | Monoclonal |
Host : | Human IgG1 Clone #Hu111 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
Clonality : | Monoclonal |
Host : | Human IgG1 Clone #Hu111 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #922137 |
Applications : | Block/Neutralize |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #63828 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #63828 |
Applications : | Flow Cytometry |