Sign In / Register
CTLA-4: Antibodies
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
52 results for "CTLA-4 Primary Antibodies" in Products
Search
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
CTLA-4: Antibodies
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
52 results for "CTLA-4 Primary Antibodies" in Products
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #48815 |
| Applications : | Western Blot |
Recombinant Monoclonal Antibody For Research Use Only
| Clonality : | Monoclonal |
| Host : | Human IgG1 Clone #Hu111 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Capture, Western Blot |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188B |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188A |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #63828 |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
| Clonality : | Monoclonal |
| Host : | Human IgG1 Clone #Hu111 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #922101 |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188A |
| Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1003705 |
| Applications : | Functional Assay, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188A |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188B |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
| Clonality : | Monoclonal |
| Host : | Human IgG1 Clone #Hu111 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2188A |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
| Clonality : | Monoclonal |
| Host : | Human IgG1 Clone #Hu111 |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
| Clonality : | Monoclonal |
| Host : | Human IgG1 Clone #Hu111 |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody For Research Use Only
| Clonality : | Monoclonal |
| Host : | Human IgG1 Clone #Hu111 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #922137 |
| Applications : | Block/Neutralize |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #63828 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #63828 |
| Applications : | Flow Cytometry |
