Chemokine Receptor Antagonists: Small Molecules and Peptides
32 results for "Chemokine Receptor Antagonists Small Molecules and Peptides" in Products
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Chemokine Receptor Antagonists: Small Molecules and Peptides
32 results for "Chemokine Receptor Antagonists Small Molecules and Peptides" in Products
Selective CCR5 antagonist
Alternate Names : | UK-427857 |
Chemical Name : | 4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide |
Purity : | ≥99% (HPLC) |
Potent and selective CXCR2 antagonist
Chemical Name : | N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea |
Purity : | ≥99% (HPLC) |
Highly selective CXCR4 antagonist
Alternate Names : | JM 3100, Plerixafor |
Chemical Name : | 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride |
Potent and selective CXCR3 antagonist
Chemical Name : | N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)benzeneacetamide |
Purity : | ≥98% (HPLC) |
High affinity, potent CCR2 antagonist
Chemical Name : | 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide |
Purity : | ≥98% (HPLC) |
Potent and selective CXCR4 antagonist
Chemical Name : | N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide |
Purity : | ≥97% (HPLC) |
CXCR3 antagonist; inhibits cell migration and metastasis
Chemical Name : | N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide |
Purity : | ≥98% (HPLC) |
Potent CXCR4 antagonist
Chemical Name : | N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride |
Purity : | ≥99% (HPLC) |
Highly selective CCR2 chemokine receptor antagonist
Chemical Name : | 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one |
Purity : | ≥99% (HPLC) |
Highly potent CXCR4 antagonist; inhibits HIV-1 replication
Chemical Name : | N1-[[4-[[(1H-Imidazol-2-ylmethyl)[(1-methyl-1H-imidazol-2-yl)methyl]amino]methyl]phenyl]methyl]-N1-methyl-N4,N4-dipropyl-1,4-butanediamine trihydrochloride |
Purity : | ≥98% (HPLC) |
Potent CXCR1 and CXCR2 allosteric antagonist
Alternate Names : | Repertaxin L-lysine salt |
Chemical Name : | (αR)-α-Methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide L-Lysine salt |
Purity : | ≥98% (HPLC) |
Potent, selective CCR1 antagonist
Alternate Names : | ZK-811752 |
Chemical Name : | (2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine |
Purity : | ≥98% (HPLC) |
Selective CCR2 antagonist
Chemical Name : | N-[2-[[(3R)-1-[trans-4-Hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-benzamide dimethanesulfonate |
Purity : | ≥98% (HPLC) |
Potent CXCR2 antagonist
Chemical Name : | 5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one |
Purity : | ≥98% (HPLC) |
Potent CCR1 chemokine receptor antagonist
Chemical Name : | 1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide |
Purity : | ≥98% (HPLC) |
Potent CCR4 antagonist
Chemical Name : | N-[[3-[[3-[[(5-Chloro-2-thienyl)sulfonyl]amino]-4-methoxy-1H-indazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide |
Purity : | ≥98% (HPLC) |
Potent CCR4 antagonist
Chemical Name : | 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride |
Purity : | ≥99% (HPLC) |
Potent CXCR2 antagonist
Chemical Name : | N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea |
Purity : | ≥98% (HPLC) |
Potent and selective CCR4 antagonist
Chemical Name : | 2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide |
Purity : | ≥98% (HPLC) |
Selective CCR1 antagonist
Alternate Names : | VUF 2274 |
Chemical Name : | 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile hydrochloride |
Purity : | ≥99% (HPLC) |
CX3CR1 antagonist
Chemical Name : | 5-[3-[4-(4-Chlorophenyl)-1-piperidinyl]propyl]pyrrolo[1,2-a]quinoxalin-4(5H)-one hydrochloride |
Purity : | ≥98% (HPLC) |
Potent CXCR2 antagonist
Chemical Name : | 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide |
Purity : | ≥98% (HPLC) |