28 results for "Chemokine Receptor Antagonists" in Products
Chemokine Receptor Antagonists Products
Chemokine receptors are found predominantly on leukocytes and are important in leukocyte trafficking, as well as leukocyte-dependent processes such as immune surveillance, immune response and pathological inflammation. Chemokines have a role in angiogenesis, apoptosis, T-cell differentiation and phagocyte activation, while inappropriate or prolonged expression of chemokines and their receptors can lead to autoimmune disease by incorrectly targeting self antigens for destruction by cytotoxic ...
Highly selective CCR2 chemokine receptor antagonist
| Chemical Name: | 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR5 and CCR2 chemokine receptor antagonist
| Chemical Name: | N-[[4-[[[6,7-Dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N,N-dimethyl-2H-pyran-4-aminium chloride |
| Purity: | ≥98% (HPLC) |
CCR2b chemokine receptor antagonist
| Chemical Name: | 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent CCR1 chemokine receptor antagonist
| Chemical Name: | 1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide |
| Purity: | ≥98% (HPLC) |
Potent, selective CCR1 antagonist
| Alternate Names: | ZK-811752 |
| Chemical Name: | (2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine |
| Purity: | ≥98% (HPLC) |
Potent and selective CXCR2 antagonist
| Chemical Name: | N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea |
| Purity: | ≥98% (HPLC) |
Selective CCR5 antagonist
| Alternate Names: | UK-427857 |
| Chemical Name: | 4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide |
| Purity: | ≥98% (HPLC) |
Highly selective CXCR4 antagonist
| Alternate Names: | JM 3100,Plerixafor |
| Chemical Name: | 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride |
CXCR3 antagonist; inhibits cell migration and metastasis
| Chemical Name: | N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide |
| Purity: | ≥98% (HPLC) |
High affinity, potent CCR2 antagonist
| Chemical Name: | 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide |
| Purity: | ≥98% (HPLC) |
Potent CXCR2 antagonist
| Chemical Name: | N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea |
| Purity: | ≥98% (HPLC) |
Potent CCR4 antagonist
| Chemical Name: | 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR3 antagonist
| Chemical Name: | N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalanine methyl ester |
| Purity: | ≥98% (HPLC) |
Selective CCR1 antagonist
| Alternate Names: | VUF 2274 |
| Chemical Name: | 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile hydrochloride |
| Purity: | ≥98% (HPLC) |
CXCR4 antagonist; antitumor
| Purity: | ≥95% (HPLC) |
Potent CCR1 and CCR3 antagonist
| Chemical Name: | 1,4-trans-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide |
| Purity: | ≥98% (HPLC) |
Potent and selective CXCR4 antagonist
| Chemical Name: | N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide |
| Purity: | ≥97% (HPLC) |
Potent and selective CXCR3 antagonist
| Chemical Name: | N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)benzeneacetamide |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR3 antagonist
| Chemical Name: | N-Benzoyl-4-nitroaniline ethyl ester |
| Purity: | ≥98% (HPLC) |
Potent CXCR4 antagonist
| Chemical Name: | N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent CXCR2 antagonist
| Chemical Name: | 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR4 antagonist
| Chemical Name: | 2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
CX3CR1 antagonist
| Chemical Name: | 5-[3-[4-(4-Chlorophenyl)-1-piperidinyl]propyl]pyrrolo[1,2-a]quinoxalin-4(5H)-one hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective CCR10 antagonist
| Chemical Name: | N-[(1R)-3-(2-Cyano-1H-pyrrol-1-yl)-1-[(4-methyl-1-piperidinyl)carbonyl]propyl]-1H-indole-4-sulfonamide |
| Purity: | ≥98% (HPLC) |
Potent CCR4 antagonist
| Chemical Name: | N-[[3-[[3-[[(5-Chloro-2-thienyl)sulfonyl]amino]-4-methoxy-1H-indazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide |
| Purity: | ≥98% (HPLC) |
