Cannabinoid R1/CB1/CNR1: Small Molecules and Peptides
Cannabinoid Receptors are seven-pass transmembrane proteins that belong to the rhodopsin family of G protein-coupled receptors. There are at least two types of Cannabinoid receptors, CB1R and CB2R, which are activated by a family of endogenous arachidonic acid derivatives, such as the endocannabinoids and D9-THC. CB1R is expressed in the central nervous system and upper GI tract, while CB2R is expressed by selected neuronal cell types and hematopoietic cells.
14 results for "Cannabinoid R1/CB1/CNR1 Small Molecules and Peptides" in Products
14 results for "Cannabinoid R1/CB1/CNR1 Small Molecules and Peptides" in Products
Cannabinoid R1/CB1/CNR1: Small Molecules and Peptides
Cannabinoid Receptors are seven-pass transmembrane proteins that belong to the rhodopsin family of G protein-coupled receptors. There are at least two types of Cannabinoid receptors, CB1R and CB2R, which are activated by a family of endogenous arachidonic acid derivatives, such as the endocannabinoids and D9-THC. CB1R is expressed in the central nervous system and upper GI tract, while CB2R is expressed by selected neuronal cell types and hematopoietic cells.
Endogenous and non-selective CB agonist; potent GPR55 agonist
| Alternate Names: | 2-AG,Arachidonoylglycerol |
| Chemical Name: | (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester |
Potent CB1 antagonist; also GPR55 agonist
| Chemical Name: | N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Endogenous and non-selective CB agonist
| Alternate Names: | Arachidonylethanolamide,AEA |
| Chemical Name: | N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Purity: | ≥98% (HPLC) |
Potent and highly selective CB1 agonist
| Alternate Names: | Arachidonyl-2'-chloroethylamide |
| Chemical Name: | N-(2-Chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Purity: | ≥97% (HPLC) |
Selective high affinity CB2 agonist
| Alternate Names: | (R)-(+)-WIN 55212 |
| Chemical Name: | (R)-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone mesylate |
| Purity: | ≥98% (HPLC) |
Highly potent CB1 inverse agonist; peripherally restricted
| Chemical Name: | 1-(2,4-Dichlorophenyl)-4-ethyl-N-1-piperidinyl-5-[5-[2-[4-(trifluoromethyl)phenyl]ethynyl]-2-thienyl]-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Ultra-high affinity and selective CB1 antagonist
| Chemical Name: | 8-Chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinyl-benzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Selective CB1 inverse agonist
| Alternate Names: | Rimonabant hydrochloride |
| Chemical Name: | N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
CB1 antagonist
| Chemical Name: | 1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective CB1 inverse agonist
High affinity and selective CB1 antagonist
| Chemical Name: | 5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
High affinity and selective CB1 antagonist
| Chemical Name: | 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Negative allosteric modulator of CB1 receptors
| Chemical Name: | N-(4-Chlorophenyl)-N'-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]urea |
| Purity: | ≥98% (HPLC) |
Cannabinoid receptor partial agonist
| Chemical Name: | 2-[(2E)-3,7-Dimethyl-2,6-octadienyl)-5-pentyl-1,3-benzenediol |
| Purity: | ≥95% (HPLC) |
