ACEA

Tocris Bioscience, part of Bio-Techne | Catalog # 1319

COA / SDS

Potent and highly selective CB1 agonist

Key Product Details

Description:	Potent and highly selective CB₁ agonist
Alternative Names:	Arachidonyl-2'-chloroethylamide
Chemical Name:	N-(2-Chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Purity:	≥97% (HPLC)
Molecular Weight:	365.99

View Full Technical Details for ACEA

Technical Data
Citations

Biological Activity for ACEA

ACEA is a potent and highly selective CB₁ receptor agonist (K_i = 1.4 nM). Displays >1400-fold selectivity over CB₂ receptors. Active in vivo.

Technical Data for ACEA

M. Wt	365.99
Formula	C₂₂H₃₆ClNO
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	220556-69-4
PubChem ID	5311006
InChi Key	SCJNCDSAIRBRIA-DOFZRALJSA-N
Smiles	O=C(NCCCl)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for ACEA

Solubility

Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)

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References for ACEA

References are publications that support the biological activity of the product.

Pertwee Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 1999 PMID: 10469884
Patel Cannabinoid CB1 receptor agonists produce cerebellar dysfunction in mice. J.Pharmacol.Exp.Ther. 2001 PMID: 11303052
Hillard Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J.Pharmacol.Exp.Ther. 1999 PMID: 10336536