Cannabigerol

Name: Cannabigerol
Brand: Tocris Bioscience
SKU: 3021
Price: 301 USD

Tocris Bioscience a Bio-Techne Brand

Catalog # 3021

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Key Product Details

Description:	Cannabinoid receptor partial agonist
Chemical Name:	2-[(2E)-3,7-Dimethyl-2,6-octadienyl)-5-pentyl-1,3-benzenediol
Purity:	≥95% (HPLC)
Molecular Weight:	316.48

View Full Technical Details for Cannabigerol

Biological Activity for Cannabigerol

Cannabigerol is a partial agonist of CB₂ and CB₁ receptors (K_i values are 337 and 440 nM respectively). Also exhibits α₂-adrenoceptor agonist activity (EC₅₀ = 0.2 nM in mouse brain membranes).

Technical Data for Cannabigerol

M. Wt	316.48
Formula	C₂₁H₃₂O₂
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	25654-31-3
PubChem ID	5315659
InChi Key	QXACEHWTBCFNSA-SFQUDFHCSA-N
Smiles	OC(C=C(CCCCC)C=C1O)=C1C/C=C(C)/CC/C=C(C)\C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Cannabigerol

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	31.65	100
	DMSO	31.65	100

Preparing Stock Solutions for Cannabigerol

The following data is based on the product molecular weight 316.48.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.16 mL	15.80 mL	31.60 mL
5 mM	0.63 mL	3.16 mL	6.32 mL
10 mM	0.32 mL	1.58 mL	3.16 mL
50 mM	0.06 mL	0.32 mL	0.63 mL

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Reconstitution Calculator

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References for Cannabigerol

References are publications that support the biological activity of the product.

Cascio Evidence that the plant cannabinoid cannabigerol is a highly potent α₂-adrenoceptor agonist and moderately potent 5HT_1A receptor antagonist. Br.J.Pharmacol. 2010 PMID: 20002104
Gauson Cannabigerol behaves as a partial agonist at both CB₁ and CB₂ receptors. Symposium on the Cannabinoids
Pertwee The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. Br.J.Pharmacol. PMID: 17828291

Citations for Cannabigerol

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