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16 results for "Adenosine A2aR Small Molecules and Peptides" in Products

Adenosine A2aR: Small Molecules and Peptides

Adenosine A2A Receptor (ADORA2A, Adenosine A2aR) is one of several receptor subtypes for adenosine. The activity of Adenosine A2aR, a G protein-coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. Adenosine A2aR is abundant in basal ganglia, vasculature and platelets and is a major target of caffeine. Variability in the acute blood pressure response to coffee may be partly explained by genetic polymorphisms of the adenosine A2A receptors, including Adenosine A2aR, and alpha(2)-adrenergic receptors.

Endogenous adenosine receptor agonist

Chemical Name: 9-β-D-Ribofuranosyl-9H-purin-6-amine
Purity: ≥98% (HPLC)
Endogenous adenosine receptor agonist

High affinity adenosine agonist

Alternate Names: 5'-N-Ethylcarboxamidoadenosine
Chemical Name: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide
Purity: ≥98% (HPLC)
High affinity adenosine agonist

PDE inhibitor (non-selective)

Chemical Name: 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
PDE inhibitor (non-selective)

A2A agonist

Chemical Name: 4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid hydrochloride
Purity: ≥98% (HPLC)
A2A agonist

Potent and highly selective A2A antagonist

Chemical Name: 4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol
Purity: ≥98% (HPLC)
Potent and highly selective A2A antagonist

Potent adenosine receptor antagonist

Chemical Name: 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
Purity: ≥98% (HPLC)
Potent adenosine receptor antagonist

Potent, highly selective A2A antagonist

Chemical Name: 2-(2-Furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Purity: ≥98% (HPLC)
Potent, highly selective A2A antagonist

Adenosine receptor antagonist

Chemical Name: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
Purity: ≥98% (HPLC)
Adenosine receptor antagonist

Adenosine A2A antagonist

Chemical Name: 8-Ethoxy-9-ethyl-9H-purin-6-amine
Purity: ≥98% (HPLC)
Adenosine A2A antagonist

Adenosine receptor agonist

Alternate Names: 2-CADO
Chemical Name: 6-Amino-2-chloropurine riboside
Purity: ≥98% (HPLC)
Adenosine receptor agonist

Potent adenosine A2A agonist

Chemical Name: 4-[2-[(6-Amino-9-b-D-ribofuranosyl-9H-purin-2-yl)thio]ethyl]benzenesulfonic acid ammonium salt
Purity: ≥97% (HPLC)
Potent adenosine A2A agonist

Adenosine receptor antagonist

Alternate Names: Xanthine amine congener
Chemical Name: N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide dihydrochloride
Purity: ≥98% (HPLC)
Adenosine receptor antagonist

Potent adenosine A2A and A2B receptor partial agonist

Chemical Name: 2-Amino-4-(4-hydroxyphenyl)-6-[(1H-imidazol-2-ylmethyl)thio]-3,5-pyridinecarbonitrile
Purity: ≥98% (HPLC)
Potent adenosine A2A and A2B receptor partial agonist

Potent and selective A2A antagonist

Alternate Names: KW-6002
Chemical Name: 8-[(1E)-2-(2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
Potent and selective A2A antagonist

A1 and A2B antagonist. CNS stimulant

Chemical Name: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
A1 and A2B antagonist. CNS stimulant

Potent and selective A2A antagonist

Chemical Name: N-[2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methoxy-1-piperidinyl)-2-pyridinyl]-4-pyrimidinyl]acetamide
Purity: ≥98% (HPLC)
Potent and selective A2A antagonist
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