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18 results for "Adenosine A1R Small Molecules and Peptides" in Products

Adenosine A1R: Small Molecules and Peptides

Adenosine A1 Receptor (ADORA1, Adenosine A1R) is an adenosine receptor that belongs to the G protein-coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The Adenosine A1R inhibits adenylyl cyclase, and plays a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication.

Endogenous adenosine receptor agonist

Chemical Name: 9-β-D-Ribofuranosyl-9H-purin-6-amine
Purity: ≥98% (HPLC)
Endogenous adenosine receptor agonist

High affinity adenosine agonist

Alternate Names: 5'-N-Ethylcarboxamidoadenosine
Chemical Name: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide
Purity: ≥98% (HPLC)
High affinity adenosine agonist

Selective A1 antagonist

Chemical Name: 8-Cyclopentyl-1,3-dipropylxanthine
Purity: ≥98% (HPLC)
Selective A1 antagonist

Highly selective A1 agonist

Chemical Name: N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine
Purity: ≥98% (HPLC)
Highly selective A1 agonist

PDE inhibitor (non-selective)

Chemical Name: 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
PDE inhibitor (non-selective)

Potent adenosine receptor antagonist

Chemical Name: 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
Purity: ≥98% (HPLC)
Potent adenosine receptor antagonist

High affinity adenosine A1 receptor antagonist

Alternate Names: CPT,8-Cyclopentyltheophylline
Chemical Name: 8-Cyclopentyltheophylline
Purity: ≥98% (HPLC)
High affinity adenosine A1 receptor antagonist

Adenosine receptor antagonist

Chemical Name: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
Purity: ≥98% (HPLC)
Adenosine receptor antagonist

Adenosine receptor agonist

Alternate Names: 2-CADO
Chemical Name: 6-Amino-2-chloropurine riboside
Purity: ≥98% (HPLC)
Adenosine receptor agonist

Adenosine receptor antagonist

Alternate Names: Xanthine amine congener
Chemical Name: N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide dihydrochloride
Purity: ≥98% (HPLC)
Adenosine receptor antagonist

Highly selective and potent A1 receptor agonist

Chemical Name: 2-Chloro-N-cyclopentyl-2'-methyladenosine
Purity: ≥98% (HPLC)
Highly selective and potent A1 receptor agonist

A1 and A2B antagonist. CNS stimulant

Chemical Name: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
A1 and A2B antagonist. CNS stimulant

Positive allosteric modulator of A1 receptors

Chemical Name: (2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone
Purity: ≥98% (HPLC)
Positive allosteric modulator of A1 receptors

Potent and selective A1 agonist

Alternate Names: CCPA
Chemical Name: 2-Chloro-N-cyclopentyladenosine
Purity: ≥98% (HPLC)
Potent and selective A1 agonist

Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist

Chemical Name: [2-Amino-4-[3-(trifluoromethyl)phenyl]-3-thienyl]phenylmethanone
Purity: ≥98% (HPLC)
Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist

Selective A1 antagonist

Alternate Names: Rolofylline
Chemical Name: 8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
Selective A1 antagonist

Potent and selective A1 agonist

Chemical Name: N-Cyclohexyl-2'-O-methyladenosine
Purity: ≥99% (HPLC)
Potent and selective A1 agonist

Potent and selective A1 agonist

Alternate Names: CPA
Chemical Name: N-Cyclopentyladenosine
Purity: ≥99% (HPLC)
Potent and selective A1 agonist
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