8-Cyclopentyl-1,3-dimethylxanthine

Name: 8-Cyclopentyl-1,3-dimethylxanthine
Brand: Tocris Bioscience
SKU: 6137

Tocris Bioscience, part of Bio-Techne | Catalog # 6137

Citations (10)

COA / SDS

High affinity adenosine A1 receptor antagonist

Key Product Details

Description:	High affinity adenosine A₁ receptor antagonist
Alternative Names:	CPT,8-Cyclopentyltheophylline
Chemical Name:	8-Cyclopentyltheophylline
Purity:	≥98% (HPLC)
Molecular Weight:	248.28

View Full Technical Details for 8-Cyclopentyl-1,3-dimethylxanthine

Technical Data
Citations

Biological Activity for 8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine is a high affinity adenosine A₁ receptor antagonist (pKi = 7.5-8).

Compound Libraries for 8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for 8-Cyclopentyl-1,3-dimethylxanthine

M. Wt	248.28
Formula	C₁₂H₁₆N₄O₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	35873-49-5
PubChem ID	1917
InChi Key	SCVHFRLUNIOSGI-UHFFFAOYSA-N
Smiles	CN1C2=C(C(N(C1=O)C)=O)N=C(C3CCCC3)N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 8-Cyclopentyl-1,3-dimethylxanthine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	24.83	100
	ethanol	2.48	10

Preparing Stock Solutions for 8-Cyclopentyl-1,3-dimethylxanthine

The following data is based on the product molecular weight 248.28.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.03 mL	20.14 mL	40.28 mL
5 mM	0.81 mL	4.03 mL	8.06 mL
10 mM	0.40 mL	2.01 mL	4.03 mL
50 mM	0.08 mL	0.40 mL	0.81 mL

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Reconstitution Calculator

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References for 8-Cyclopentyl-1,3-dimethylxanthine

References are publications that support the biological activity of the product.

Dalpiaz Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A₁ receptors. Biochem.Pharmacol. 1998 PMID: 9827575