Key Product Details
Description: | Selective A1 antagonist |
Chemical Name: | 8-Cyclopentyl-1,3-dipropylxanthine |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 304.39 |
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Citations for DPCPX (45)
Citations are publications that use Bio-Techne products. Selected citations for DPCPX include:
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Liu et al.
(2018)
Adenosine binds predominantly to adenosine receptor A1 subtype in astrocytes and mediates an immunosuppressive effect.
Brain Res..
1700:47
PMID: 29935155 -
Stoddart et al.
(2015)
Application of BRET to monitor ligand binding to GPCRs.
Nat Methods.
12:661
PMID: 26030448 -
Angelantonio et al.
(2015)
Basal adenosine modulates the functional properties of AMPA receptors in mouse hippocampal neurons through the activation of A1R A2AR and A3R.
J Inflamm (Lond).
9:409
PMID: 26528137 -
Kohno et al.
(2015)
Anti-inflammatory effects of adenosine N1-oxide.
Am J Physiol Lung Cell Mol Physiol.
12:2
PMID: 25632271 -
Cunha et al.
(2015)
Creatine, similarly to KA, affords antidepressant-like effects in the tail suspension test via adenosine A1� and A2A receptor activation.
J Clin Invest.
11:215
PMID: 25702084 -
Dobson et al.
(2015)
Caffeine Modulates Vesicle Release and Recovery at Cerebellar Parallel Fibre Terminals, Independently of Calcium and Cyclic AMP Signalling.
J Neurosci.
10:e0125974
PMID: 25933382 -
Carlsen and Perrier
(2014)
Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord.
Front Neural Circuits.
8:60
PMID: 24926236 -
Li et al.
(2014)
Regulation of photoreceptor gap junction phosphorylation by adenosine in zebrafish retina.
Vis Neurosci.
31:237
PMID: 24844306 -
Ruby et al.
(2014)
Adenosinergic regulation of striatal clock gene expression and ethanol intake during constant light.
Korean J Anesthesiol.
39:2432
PMID: 24755889 -
Diógenes et al.
(2014)
Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.
Cereb Cortex.
24:67
PMID: 22997174 -
Fuss et al.
(2013)
Hippocampal serotonin-1A receptor function in a mouse model of anxiety induced by long-term voluntary wheel running.
Synapse.
67:648
PMID: 23505009 -
Augusto et al.
(2013)
Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions.
Biochim Biophys Acta.
33:11390
PMID: 23843511 -
Scianni et al.
(2013)
Fractalkine (CX3CL1) enhances hippocampal N-MthD.-aspartate receptor (NMDAR) function via D-serine and adenosine receptor type A2 (A2AR) activity.
J Neuroinflammation.
10:108
PMID: 23981568 -
Kaster et al.
(2013)
The antidepressant-like effect of inosine in the FST is associated with both adenosine A1 and A 2A receptors.
Purinergic Signal.
9:481
PMID: 23613131 -
Stoddart et al.
(2012)
Fragment screening at adenosine-A(3) receptors in living cells using a fluorescence-based binding assay.
Chem Biol.
19:1105
PMID: 22999879 -
Aitta-Aho et al.
(2012)
Importance of GluA1 subunit-containing AMPA glutamate receptors for mor. state-dependency.
PLoS One.
7:e38325
PMID: 22675452 -
Caiati et al.
(2012)
Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses.
Sci Rep.
2:285
PMID: 22368777 -
Hensler et al.
(2012)
GABAB receptor-positive modulators: brain region-dependent effects.
J Pharmacol Exp Ther.
340:19
PMID: 21954301 -
Kan et al.
(2012)
Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway.
J Virol.
86:10338
PMID: 22787201 -
Lee et al.
(2012)
Polyphenol (-)-epigallocatechin gallate-induced cardioprotection may attenuate ischemia-reperfusion injury through adenosine receptor activation: a preliminary study.
J Cell Biol.
63:340
PMID: 23115687 -
Park et al.
(2012)
A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury.
Am J Physiol Renal Physiol.
303:F721
PMID: 22759398 -
Ilie et al.
(2012)
Adenosine release during seizures attenuates GABAA receptor-mediated depolarization.
J Neurosci.
32:5321
PMID: 22496577 -
Lutz et al.
(2011)
Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic mor.
Eur Neuropsychopharmacol.
21:835
PMID: 21402471 -
Mioranzza et al.
(2011)
Blockade of adenosine A(1) receptors prevents methylphenidate-induced impairment of object recognition task in adult mice.
Prog Neuropsychopharmacol Biol Psychiatry.
35:169
PMID: 21044657 -
Sousa et al.
(2011)
Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of δ9-tetrahydrocannabinol on spatial memory.
Neuropsychopharmacology.
36:472
PMID: 20927050 -
Burbassi et al.
(2010)
Alterations of CXCR4 function in μ-opioid receptor-deficient glia.
Eur J Neurosci.
32:1278
PMID: 20880358 -
Long et al.
(2010)
Adenosine receptor regulation of coronary blood flow in Ossabaw miniature swine.
Proc Natl Acad Sci U S A.
335:781
PMID: 20855445 -
Thakkar et al.
(2010)
Role of wake-promoting basal forebrain and adenosinergic mechanisms in sleep-promoting effects of ethanol.
Alcohol Clin Exp Res.
34:997
PMID: 20374215 -
Yang et al.
(2010)
Adenosine mediated desensitization of cAMP signaling enhances T-cell responses.
Eur J Immunol.
40:449
PMID: 19950175 -
Epperson et al.
(2009)
Adenosine receptors and second messenger signaling pathways in rat cardiac fibroblasts.
Am J Physiol Cell Physiol.
296:C1171
PMID: 19244482 -
Xi et al.
(2009)
Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts.
J Mol Cell Cardiol.
47:684
PMID: 19695259 -
Clark et al.
(2009)
Adenosine-evoked hyperpolarization of retinal ganglion cells is mediated by G-protein-coupled inwardly rectifying K+ and small conductance Ca2+-activated K+ channel activation.
J Neurosci.
29:11237
PMID: 19741130 -
Yu et al.
(2009)
Effect of ventilation pressure on alveolar fluid clearance and β-agonist responses in mice.
Neuropsychopharmacology.
297:L785
PMID: 19684202 -
Rex et al.
(2009)
Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation.
Am J Respir Crit Care Med.
186:85
PMID: 19596849 -
Maeda and Koos
(2009)
Adenosine A1 and A2a receptors modulate Insemia, glycemia, and lactatemia in fetal sheep.
Purinergic Signal.
296:R693
PMID: 19118101 -
Burbassi et al.
(2008)
GTPgammaS incorporation in the rat brain: a study on mu-opioid receptors and CXCR4.
J Neuroimmune Pharmacol.
3:26
PMID: 18247130 -
Wolk et al.
(2008)
Influenza A virus inhibits alveolar fluid clearance in BALB/c mice.
Am J Physiol Regul Integr Comp Physiol.
178:969
PMID: 18689466 -
Eckle et al.
(2008)
A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice.
J Neurosci.
118:3301
PMID: 18787641 -
Bhanu et al.
(2008)
Inhibition of erythroblast growth and fetal hemoglobin production by ribofuranose-substituted adenosine derivatives.
PLoS One.
1782:504
PMID: 18586086 -
Satake et al.
(2006)
Characterization of AMPA receptors targeted by the climbing fiber transmitter mediating presynaptic inhibition of GABAergic transmission at cerebellar interneuron-Purkinje cell synapses.
J Neurosci.
26:2278
PMID: 16495455 -
Kornerup et al.
(2005)
Pharmacological characterisation of the adenosine receptor mediating increased ion transport in the mouse isolated trachea and the effect of allergen challenge.
Br J Pharmacol.
144:1011
PMID: 15685200 -
Newman
(2005)
Calcium increases in retinal glial cells evoked by light-induced neuronal activity.
Front Cell Neurosci.
25:5502
PMID: 15944378 -
Rex et al.
(2005)
Long-term potentiation is impaired in middle-aged rats: regional specificity and reversal by adenosine receptor antagonists.
J Neurosci.
25:5956
PMID: 15976084 -
Melyan et al.
(2004)
Metabotropic regulation of intrinsic excitability by synaptic activation of kainate receptors.
J Neurosci.
24:4530
PMID: 15140923 -
Moore et al.
(2003)
Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses.
J Neurosci.
100:14397
PMID: 14608033
There are no citations that match your criteria.