Additional Apoptosis-related Compounds Small Molecules and Peptides

Selective LPA2 receptor non-lipid agonist

Antimalarial; inhibits apoptosis and autophagy

Mitochondrial VDAC modulator; also Ferroptosis activator

Non-selective PI 3-kinase inhibitor

Selective inhibitor of erastin induced ferroptosis

Class III PI 3-kinase inhibitor; also inhibits autophagy

Necroptosis inhibitor; also inhibits pyroptosis

VGF-derived peptide

Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis

Potent ferroptosis inhibitor

Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Potent and metabolically stable RIP1 kinase inhibitor

Potent and selective PD-1/PD-L1 interaction inhibitor

Peptide inhibitor of the PD-1 signaling pathway

Potent and selective PD-1/PD-L1 interaction inhibitor