3-Methyladenine

Tocris Bioscience, part of Bio-Techne | Catalog # 3977

Class III PI 3-kinase inhibitor; also inhibits autophagy
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Key Product Details

Description

Class III PI 3-kinase inhibitor; also inhibits autophagy

Alternative Names

3-MA

View all PI 3-Kinase Inhibitors »

Product Description

3-Methyladenine is an inhibitor of class III phosphatidylinositol 3-kinase (PI 3-kinase); also inhibits the autophagic sequestration of cell proteins in rat hepatocytes. Blocks apoptosis in cerebellar granule cells (CGCs) following serum and potassium deprivation.

Product Specifications

Molecular Weight

149.15

Formula

C6H7N5

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

3-Methyl-3H-purin-6-amine

CAS Number

5142-23-4

PubChem ID

1673

InChI Key

FSASIHFSFGAIJM-UHFFFAOYSA-N

SMILES

NC(N=CN2C)=C1C2=NC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 2.98 20

Preparing Stock Solutions for 3-Methyladenine

The following data is based on the product molecular weight 149.15

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 33.52 mL 167.62 mL 335.23 mL
1 mM 6.70 mL 33.52 mL 67.05 mL
2 mM 3.35 mL 16.76 mL 33.52 mL
10 mM 0.67 mL 3.35 mL 6.70 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for 3-Methyladenine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 3-Methyladenine

For research use only

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