TLQP 21

Name: TLQP 21
Brand: Tocris Bioscience
SKU: 3051

Tocris Bioscience, part of Bio-Techne | Catalog # 3051

Citations (7)

COA / SDS

VGF-derived peptide

Key Product Details

Description:	VGF-derived peptide
Purity:	≥95% (HPLC)
Molecular Weight:	2432.77

View Full Technical Details for TLQP 21

Technical Data
Citations

Biological Activity for TLQP 21

TLQP 21 is a VGF-derived peptide; spans residues 556-576 of the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. Increases energy expenditure and prevents early phase diet-induced diabetes.

Technical Data for TLQP 21

M. Wt	2432.77
Formula	C₁₀₇H₁₇₀N₄₀O₂₆
Single Letter Sequence	TLQPPASSRRRHFHHALPPAR
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	869988-94-3
PubChem ID	16158480
InChi Key	PWWMOXVVMRPYJS-IWCKOKPFSA-N
Smiles	[H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for TLQP 21

Solubility

Soluble to 1mg/ml in water

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References for TLQP 21

References are publications that support the biological activity of the product.

Bartolomucci TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity. Proc.Natl.Acad.Sci. USA
Jethwa VGF-derived peptide, TLQP-21, regulates food intake and body weight in Siberian hamsters. Endocrinol.
Severini TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cell death induced by serum and potassium deprivation. J.Neurochem. 2008 PMID: 18173805