29 results for "Active Degrader Negative Controls" in Products

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Active Degrader Negative Controls Products

ARCC 4 negative control

Catalog #: 7255
Citations (1)
Product Documents

Negative control for ARCC 4 (Cat. No. 7254)

Chemical Name: (2S,4S)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98% (HPLC)
Negative control for ARCC 4 (Cat. No. 7254)

N-methylated pomalidomide

Catalog #: 7716
Product Documents

Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control

Chemical Name: 4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity: ≥95% (HPLC)
Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control

dTAGV-1-NEG

Catalog #: 6915
Citations (9)
Product Documents

Negative control for dTAGV-1 (Cat. No. 6914)

Chemical Name: (R)-3-(3,4-Dimethoxyphenyl)-1-(2-(2-((7-(((S)-1-((2R,4S)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptyl)amino)-2-oxoethoxy)phenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate
Purity: ≥98% (HPLC)
Negative control for dTAGV-1 (Cat. No. 6914)

STING Degrader N-Me-SP23

Catalog #: 8054
Citations (1)
Product Documents

Negative control for STING Degrader SP23 (Cat. No. 8053)

Chemical Name: (2E)-N1-[6-[[2,3-Dihydro-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide
Purity: ≥98% (HPLC)
Negative control for STING Degrader SP23 (Cat. No. 8053)

α-Synuclein Degrader 2bn

Catalog #: 8041
Product Documents

Negative control for α Synuclein Degrader 2b (Cat. No. 8040)

Chemical Name: 2-[[3-[5-(1,3-Benzodioxol-5-yl)-1H-pyrazol-3-yl]phenyl]amino]-N-[2-[2-[2-[2-[[2-(1-methyl-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]acetamide
Purity: ≥98% (HPLC)
Negative control for α Synuclein Degrader 2b (Cat. No. 8040)

dTAG-13-NEG

Catalog #: 6916
Citations (2)
Product Documents

Negative control for dTAG-13 (Cat. No. 6605)

Chemical Name: 1-[(2S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-(2S)-2-piperidinecarboxylate (1R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(1-methyl-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester
Purity: ≥97% (HPLC)
Negative control for dTAG-13 (Cat. No. 6605)

CG 858-Neg

Catalog #: 7428
Product Documents

Negative control for CG 858 (Cat. No. 7427)

Chemical Name: N-[[4-[3-[2,6-Difluoro-3-[(propylsulfonyl)amino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]methyl]-5-[[2-(1-methyl-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]pentanamide
Purity: ≥98% (HPLC)
Negative control for CG 858 (Cat. No. 7427)

dTAG-47-NEG

Catalog #: 7531
Product Documents

Negative control for dTAG-47 (Cat. No. 7530)

Chemical Name: (1R)-3-(3,4-Dimethoxyphenyl)-1-(2-(2-((8-((1,3-dioxo-2-(2-oxopiperidin-3-yl)isoindolin-5-yl)amino)octyl)amino)-2-oxoethoxy)phenyl)propyl (2S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate
Purity: ≥97% (HPLC)
Negative control for dTAG-47 (Cat. No. 7530)

SK 575-NEG

Catalog #: 7588
Product Documents

Negative control for SK 575 (Cat. No. 7583)

Chemical Name: 12-(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-N-(2-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-12-oxododecanamide
Purity: ≥98% (HPLC)
Negative control for SK 575 (Cat. No. 7583)

CG 428-Neg

Catalog #: 7426
Product Documents

Negative control for CG 428 (Cat. No. 7425)

Chemical Name: 2-(1-Methyl-2,6-dioxo-3-piperidinyl)-4-[[2-[3-[4-[6-[6-[(2R)-2-(3-fluorophenyl)-1-pyrrolidinyl]imidazo[1,2-b]pyridazin-3-yl]-2-pyridinyl]-1-piperazinyl]-3-oxopropoxy]ethyl]amino]-1H-isoindole-1,3(2H)-dione
Purity: ≥98% (HPLC)
Negative control for CG 428 (Cat. No. 7425)

aTAG 2139-NEG

Catalog #: 7575
Product Documents

Negative control for aTAG 2139 (Cat. No. 6970)

Chemical Name: 6-(6-((4-(2-((2-(1-Methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)carbamoyl)pyridin-3-yl)-N-methyl-4-(phenylamino)quinoline-3-carboxamide
Purity: ≥98% (HPLC)
Negative control for aTAG 2139 (Cat. no. 6970)

TBK1 control PROTAC® 4

Catalog #: 7260
Citations (3)
Product Documents

Negative control for TBK1 PROTAC® 3i (Cat. No. 7259)

Chemical Name: (2S,4S)-1-((S)-18-(4-((5-Bromo-4-((3-(N-methylcyclobutanecarboxamido)propyl)amino)pyrimidin-2-yl)amino)phenoxy)-2-(tert-butyl)-4-oxo-6,10,15-trioxa-3-azaoctadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98% (HPLC)
Negative control for TBK1 PROTAC® 3i (Cat. No. 7259)

PROTAC®(H-PGDS)-8

Catalog #: 8005
Product Documents

Negative control for PROTAC®(H-PGDS)-7 (Cat. No. 8004)

Chemical Name: N-[4-[4-[[4-[2,3-Dihydro-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1,3-dioxo-1H-isoindol-4-yl]-1-piperazinyl]carbonyl]-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide
Purity: ≥98% (HPLC)
Negative control for PROTAC®(H-PGDS)-7 (Cat. No. 8004)

cis VH 032, amine dihydrochloride

Catalog #: 6969
Product Documents

Negative control for VH 032, amine (Cat. No. 6462)

Alternate Names: (S,S,S)-AHPC
Chemical Name: (2S,4S)-1-[(2S)-2-Amino-3,3-dimethyl-butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide dihydrochloride
Purity: ≥98% (HPLC)
Negative control for VH 032, amine (Cat. No. 6462)

cis MZ 1

Catalog #: 6155
Citations (1)
Product Documents

Negative Control for MZ 1 (Cat. No. 6154)

Chemical Name: (2S,4S)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)- 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98% (HPLC)
Negative Control for MZ 1 (Cat. No. 6154)

TL 13-27

Catalog #: 6525
Product Documents

Negative control for TL 12-186 (Cat. No. 6524)

Chemical Name: N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((1,3-dioxo-2-(2-oxopiperidin-3-yl)isoindolin-4-yl)amino)acetamide
Purity: ≥98% (HPLC)
Negative control for TL 12-186 (Cat. No. 6524)

MS 154N

Catalog #: 7396
Product Documents

Negative control for MS 154 (Cat No. 7395)

Chemical Name: 3-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-N-(8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)octyl)propanamide
Purity: ≥98% (HPLC)
Negative control for MS 154 (Cat No. 7395)

cis-SIM1

Catalog #: 7433
Product Documents

Negative control for SIM1 (Cat. No. 7432)

Chemical Name: N,N'-(11-((2-(((S)-1-((2S,4S)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)methyl)-11-methyl-3,6,9,13,16,19-hexaoxahenicosane-1,21-diyl)bis(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide)
Purity: ≥98% (HPLC)
Negative control for SIM1 (Cat. No. 7432)

MS 39N

Catalog #: 7398
Product Documents

Negative control for MS 39 (Cat. No. 7397)

Chemical Name: (2R,4S)-1-((S)-2-(11-(4-(3-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)piperazin-1-yl)-11-oxoundecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98% (HPLC)
Negative control for MS 39 (Cat. No. 7397)

cis-VZ 185

Catalog #: 6939
Product Documents

Negative control for VZ 185 (Cat. No. 6936)

Chemical Name: (2S,4S)-N-(2-((5-(4-(2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)piperazin-1-yl)pentyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide
Purity: ≥95% (HPLC)
Negative control for VZ 185 (Cat. No. 6936)

TL 13-110

Catalog #: 6746
Product Documents

Negative control for TL 13-112 (Cat. No. 6745)

Chemical Name: N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)ethoxy)ethoxy)ethyl)-2-((1,3-dioxo-2-(2-oxopiperidin-3-yl)isoindolin-4-yl)amino)acetamide
Purity: ≥98% (HPLC)
Negative control for TL 13-112 (Cat. No. 6745)

MD15

Catalog #: 7504
Product Documents

Negative control for MD13 (Cat. No. 7503)

Chemical Name: N-(4-(7-Hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)-8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanamide
Purity: ≥98% (HPLC)
Negative control for MD13 (Cat. No. 7503)

(+)-JQ1 bump-N, acid functionalized

Catalog #: 8827
Product Documents

Negative control for (+)-JQ1 bump, acid functionalized (Cat. No. 7689)

Chemical Name: (S)-2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoic acid
Purity: ≥98% (HPLC)
Negative control for (+)-JQ1 bump, acid functionalized (Cat. No. 7689)

TL 13-22

Catalog #: 6747
Product Documents

Negative control for TL 13-12 (Cat. No. 6744)

Chemical Name: N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((1,3-dioxo-2-(2-oxopiperidin-3-yl)isoindolin-4-yl)amino)acetamide
Purity: ≥98% (HPLC)
Negative control for TL 13-12 (Cat. No. 6744)

LC 2 Epimer

Catalog #: 7421
Citations (1)
Product Documents

Negative control for LC 2 (Cat. No. 7420)

Chemical Name: (2S,4S)-1-((S)-2-(3-(3-((S)-2-(((7-(8-Chloronaphthalen-1-yl)-4-((S)-3-(cyanomethyl)-4-(2-fluoroacryloyl)piperazin-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)oxy)methyl)pyrrolidin-1-yl)propoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥95% (HPLC)
Negative control for LC 2 (Cat. No. 7420)
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