cis MZ 1
Tocris Bioscience, part of Bio-Techne | Catalog # 6155
Negative Control for MZ 1 (Cat. No. 6154)
Key Product Details
Description
Negative Control for MZ 1 (Cat. No. 6154)
Product Description
cis MZ 1 is a negative Control for MZ1 (Cat.No. 6154). Exhibits no significant VHL binding affinity.Licensing Information
Sold under licence from the University of DundeeExternal Portal Information
Chemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of MZ 1 is reviewed on the chemical probes website.Product Specifications
Molecular Weight
1002.64
Formula
C49H60ClN9O8S2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(2S,4S)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)- 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CAS Number
1797406-72-4
PubChem ID
124201820
InChI Key
PTAMRJLIOCHJMQ-HADAFJFFSA-N
SMILES
CC1=C(C2=C(N3C(C)=NN=C3[C@@H](N=C2C4=CC=C(C=C4)Cl)CC(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N5C[C@H](C[C@H]5C(NCC6=CC=C(C7=C(N=CS7)C)C=C6)=O)O)=O)=O)=O)S1)C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 100.26 | 100 | |
| Ethanol | 100.26 | 100 |
Preparing Stock Solutions
for cis MZ 1
The following data is based on the product molecular weight 1002.64
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.00 mL | 4.99 mL | 9.97 mL |
| 5 mM | 0.20 mL | 1.00 mL | 1.99 mL |
| 10 mM | 0.10 mL | 0.50 mL | 1.00 mL |
| 50 mM | 0.02 mL | 0.10 mL | 0.20 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Zengerle Selective small molecule induced degradation of the BET bromodomain protein BRD4. ACS.Chem.Biol. 2015 PMID: 26035625
Product Specific Notices for cis MZ 1
For research use only
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