dTAG-13-NEG
Tocris Bioscience, part of Bio-Techne | Catalog # 6916
Negative control for dTAG-13 (Cat. No. 6605)
Key Product Details
Description
Negative control for dTAG-13 (Cat. No. 6605)
Product Description
dTAG-13-NEG is a negative control for dTAG-13 (Cat. No. 6605).Licensing Information
Sold under license from Dana-Farber Cancer InstituteProduct Specifications
Molecular Weight
1063.19
Formula
C58H70N4O15
Storage
Store at -20°C
Purity
≥97% (HPLC)
Chemical Name
1-[(2S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-(2S)-2-piperidinecarboxylate (1R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(1-methyl-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester
CAS Number
2451573-90-1
InChI Key
ZKVNXENIWGNDDO-SKTJQTJUSA-N
SMILES
CC[C@@H](C1=CC(OC)=C(C(OC)=C1)OC)C(N2CCCC[C@H]2C(O[C@@H](C3=CC=CC=C3OCC(NCCCCCCOC4=CC=CC(C(N5C6CCC(N(C)C6=O)=O)=O)=C4C5=O)=O)CCC7=CC(OC)=C(C=C7)OC)=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 106.32 | 100 | |
| Ethanol | 21.26 | 20 |
Preparing Stock Solutions
for dTAG-13-NEG
The following data is based on the product molecular weight 1063.19
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.94 mL | 4.70 mL | 9.41 mL |
| 5 mM | 0.19 mL | 0.94 mL | 1.88 mL |
| 10 mM | 0.09 mL | 0.47 mL | 0.94 mL |
| 50 mM | 0.02 mL | 0.09 mL | 0.19 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Nabet The dTAG system for immediate and target-specific protein degradation. Nat.Chem.Biol. 2018 PMID: 29581585
- Nabet Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules. Nat.Commun. 2020 PMID: 32948771
Product Specific Notices for dTAG-13-NEG
For research use only
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