CG 858-Neg
Tocris Bioscience, part of Bio-Techne | Catalog # 7428
Negative control for CG 858 (Cat. No. 7427)
Key Product Details
Description
Negative control for CG 858 (Cat. No. 7427)
Product Description
Negative control for CG 858 (Cat. No. 7427)Licensing Information
Sold under license from CullgenProduct Specifications
Molecular Weight
853.90
Formula
C43H41F2N7O8S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-[[4-[3-[2,6-Difluoro-3-[(propylsulfonyl)amino]benzoyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]methyl]-5-[[2-(1-methyl-2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]pentanamide
CAS Number
2417296-83-2
PubChem ID
155520701
InChI Key
KMSYZOWKSVQANC-UHFFFAOYSA-N
SMILES
CCCS(=O)(NC1=CC=C(C(C(C2=CNC3=NC=C(C4=CC=C(C=C4)CNC(CCCCNC5=CC=C6C(N(C(C6=C5)=O)C7CCC(N(C)C7=O)=O)=O)=O)C=C23)=O)=C1F)F)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 85.39 | 100 |
Preparing Stock Solutions
for CG 858-Neg
The following data is based on the product molecular weight 853.90
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.17 mL | 5.86 mL | 11.71 mL |
| 5 mM | 0.23 mL | 1.17 mL | 2.34 mL |
| 10 mM | 0.12 mL | 0.59 mL | 1.17 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Han Discovery of selective small molecule degraders of BRAF-V600E. J.Med.Chem. 2020 PMID: 32223235
Product Specific Notices for CG 858-Neg
For research use only
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