STING Degrader N-Me-SP23
Tocris Bioscience, part of Bio-Techne | Catalog # 8054
Negative control for STING Degrader SP23 (Cat. No. 8053)
Key Product Details
Description
Negative control for STING Degrader SP23 (Cat. No. 8053)
Product Description
STING Degrader N-Me-SP23 is a negative control for STING Degrader SP23 (Cat. No. 8053).Product Specifications
Molecular Weight
713.70
Formula
C35H35N7O10
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(2E)-N1-[6-[[2,3-Dihydro-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide
CAS Number
2767427-87-0
InChI Key
GLXVESPMAQKDPG-FOCLMDBBSA-N
SMILES
O=C1C2=C(NCCCCCCNC(/C=C/C(NC3=CC=C(C=C3)NC(C4=CC=C(N(=O)=O)O4)=O)=O)=O)C=CC=C2C(N1C5C(N(C(CC5)=O)C)=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 71.37 | 100 |
Preparing Stock Solutions
for STING Degrader N-Me-SP23
The following data is based on the product molecular weight 713.70
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.40 mL | 7.01 mL | 14.01 mL |
| 5 mM | 0.28 mL | 1.40 mL | 2.80 mL |
| 10 mM | 0.14 mL | 0.70 mL | 1.40 mL |
| 50 mM | 0.03 mL | 0.14 mL | 0.28 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Liu Novel CRBN-recruiting proteolysis-targeting chimeras as degraders of stimulator of interferon genes with in vivo anti- inflammatory efficacy. J.Med.Chem. 2022 PMID: 35452223
Product Specific Notices for STING Degrader N-Me-SP23
For research use only
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