Human B7-H3 MAb (Clone 185504)
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity: | Human |
Immunogen: |
Mouse myeloma cell line NS0-derived recombinant human B7‑H3 Leu29-Pro245 Accession # NP_079516 |
Applications: | CyTOF-ready, Flow Cytometry, Knockout Validated, Western Blot |
Label: | Unconjugated |
Source: | Monoclonal Mouse IgG1 Clone # 185504 |
Specificity: |
Detects human B7-H3 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) B7‑H1, rhB7‑H2, rhB7‑1, rhB7‑2, or recombinant mouse PD-L2 is observed. |
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Citations for Human B7-H3 MAb (Clone 185504) (8)
Citations are publications that use Bio-Techne products. Selected citations for Human B7-H3 MAb (Clone 185504) include:
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Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryM Oroujeni et al. (2022), Evaluation of an Affibody-Based Binder for Imaging of Immune Check-Point Molecule B7-H3 Pharmaceutics, 14(9).
PMID: 36145529 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCJ Liu et al. (2021), Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal of hematology oncology, 2021;14(1):21.
PMID: 33514401 -
Species: Human
Sample Types: Cell Lysates
Applications: ImmunoprecipitationS Yang et al. (2020), Targeting B7-H3 Immune Checkpoint With Chimeric Antigen Receptor-Engineered Natural Killer Cells Exhibits Potent Cytotoxicity Against Non-Small Cell Lung Cancer Front Pharmacol, 11(0):1089.
PMID: 32848731 -
Species: Human
Sample Types: Cell Lysates
Applications: ImmunoprecipitationS Yang et al. (2020), Targeting B7-H3 Immune Checkpoint With Chimeric Antigen Receptor-Engineered Natural Killer Cells Exhibits Potent Cytotoxicity Against Non-Small Cell Lung Cancer Front Pharmacol, 11(0):1089.
PMID: 32848731 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometrySucker A et al. (2014), Genetic evolution of T-cell resistance in the course of melanoma progression. Clin Cancer Res, 20(24):6593-604.
PMID: 25294904 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryRamsay et al. (2012), Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Blood, 120(7):1412-21.
PMID: 22547582 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryTran CN et al. (2008), Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3. J. Immunol., 180(5):2989-98.
PMID: 18292521 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: Western BlotDas S et al. (2006), Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection. J. Immunol., 176(5):3000-9.
PMID: 16493058
There are no citations that match your criteria.
Customer Reviews for Human B7-H3 MAb (Clone 185504) (4)
Customer Images
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Application: WBSample Tested: Osteosarcoma U2OS cell lineSpecies: HumanVerified Customer | Posted 06/22/2022
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Application: Simple WesternSample Tested: Purified proteinSpecies: HumanVerified Customer | Posted 05/01/2020
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Application: FuncSample Tested: 3T3-L1 mouse embryonic fibroblast adipose-like cell lineSpecies: MouseVerified Customer | Posted 05/07/2019
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Application: Simple WesternSample Tested: Purified proteinSpecies: HumanVerified Customer | Posted 11/02/2018
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