Human B7-H3 Alexa Fluor® 750-conjugated Antibody

Name: Human B7-H3 Alexa Fluor® 750-conjugated Antibody
Brand: R&D Systems
SKU: FAB1027S

R&D Systems, Inc. a Bio-Techne Brand

Catalog # FAB1027S

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Key Product Details

Species Reactivity:	Human
Immunogen:	Mouse myeloma cell line NS0-derived recombinant human B7‑H3 Leu29-Pro245 Accession # NP_079516
Applications:	Flow Cytometry
Label:	Alexa Fluor 750 (Excitation=749 nm, Emission=775 nm)
Specificity:	Detects human B7-H3 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) B7‑H1, rhB7‑H2, rhB7‑1, rhB7‑2, or recombinant mouse PD-L2 is observed.

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Applications for Human B7-H3 Alexa Fluor® 750-conjugated Antibody

	Recommended Concentration	Sample
Flow Cytometry	0.25-1 µg/10⁶ cells	Human monocyte-derived dendritic cells and PC‑3 human prostate cancer cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Formulation, Preparation and Storage

Formulation	Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

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Background: B7-H3

B7-H3 is a member of the B7 family of immune co-stimulatory receptors. Its expression is induced on dendritic cells and monocytes by inflammatory cytokines.

Item	Value
Long Name	B7 Homolog 3
Entrez Gene IDs	80381 (Human); 102657 (Mouse); 315716 (Rat); 102131295 (Cynomolgus Monkey)
Alternate Names	B7-H3, B7-H3B7 homolog 3, B7H3, B7H34Ig-B7-H3, CD276, CD276 antigen, CD276 molecule, Costimulatory molecule

Product Specific Notices for Human B7-H3 Alexa Fluor® 750-conjugated Antibody

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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Human B7-H3 Alexa Fluor® 750-conjugated Antibody

R&D Systems, Inc. a Bio-Techne Brand

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Applications for Human B7-H3 Alexa Fluor® 750-conjugated Antibody

Formulation, Preparation and Storage

Plan Your Experiments

Reconstitution Calculator

Background: B7-H3

Product Specific Notices for Human B7-H3 Alexa Fluor® 750-conjugated Antibody

Citations for Human B7-H3 Alexa Fluor® 750-conjugated Antibody

Product Documents for Human B7-H3 Alexa Fluor® 750-conjugated Antibody

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