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VEGFR1/Flt-1 Products
VEGFR1 (vascular endothelial growth factor receptor 1; Flt-1) binds to VEGF-A, VEGF-B, and PlGF and functions in vasculogenesis, angiogenesis, lymphangiogenesis, and wound healing. It is expressed on endothelial cells, osteoblasts, placental trophoblasts, renal mesangial cells, and some hematopoietic stem cells. It can heterodimerize with VEGFR2 and modulate VEGFR2 mediated endothelial cell proliferation and vessel branching. VEGFR1 engagement on monocyte/macrophage lineage cells enhances their migration, and release of growth factors and cytokines.
54 results for "VEGFR1/Flt-1" in Products
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VEGFR1/Flt-1 Products
VEGFR1 (vascular endothelial growth factor receptor 1; Flt-1) binds to VEGF-A, VEGF-B, and PlGF and functions in vasculogenesis, angiogenesis, lymphangiogenesis, and wound healing. It is expressed on endothelial cells, osteoblasts, placental trophoblasts, renal mesangial cells, and some hematopoietic stem cells. It can heterodimerize with VEGFR2 and modulate VEGFR2 mediated endothelial cell proliferation and vessel branching. VEGFR1 engagement on monocyte/macrophage lineage cells enhances their migration, and release of growth factors and cytokines.
54 results for "VEGFR1/Flt-1" in Products
Catalog #:
SPCK-PANEL
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Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
ELISA
| Sensitivity : | 8.46 pg/mL |
| Assay Range : | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Applications : | ELISA |
Catalog #:
ARY012
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
WB, Flow, CyTOF-ready
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #49560 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
WB, IHC
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #141515 |
| Applications : | Immunohistochemistry, Western Blot |
Catalog #:
FAB4711R
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #141522 |
| Applications : | Flow Cytometry |
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names : | Semaxinib |
| Chemical Name : | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity : | ≥99% (HPLC) |
ELISA
| Assay Range : | 156 - 10,000 pg/mL |
| Applications : | ELISA |
WB, Flow, IHC, Block, CyTOF-ready
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
Catalog #:
FAB321R
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #49560 |
| Applications : | Flow Cytometry |
Catalog #:
MAB6564
WB
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #611926 |
| Applications : | Western Blot |
WB
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Western Blot |
Potent VEGFR-1, -2 and -3 inhibitor
| Chemical Name : | N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide |
| Purity : | ≥99% (HPLC) |
ELISA
| Sensitivity : | 15.2 pg/mL |
| Assay Range : | 125 - 8,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
| Applications : | ELISA |
BA
| Source : | Sf 21 (baculovirus) |
| Accession # : | AAC50060 |
| Applications : | Bioactivity |
Catalog #:
FABSP3P
Flow
1 vial each of PE-conjugated anti-VEGF R1 (clone 49560), VEGF R2 (clone 89106), and VEGF R3 (clone 54733)
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #89106, 49560, 54733 |
| Applications : | Flow Cytometry |
Potent VEGFR, PDGFRβ and KIT inhibitor
| Alternate Names : | SU 11248 |
| Chemical Name : | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Purity : | ≥99% (HPLC) |
ELISA
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
Catalog #:
MAB4711
WB, Flow, CyTOF-ready
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #141522 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #49560 |
| Applications : | Flow Cytometry |
Catalog #:
7756-FL
BA
| Source : | NS0 |
| Accession # : | P35969 |
| Applications : | Bioactivity |
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #141522 |
| Applications : | Flow Cytometry |
