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Protein Arginine Methyltransferase Inhibitors: Small Molecules and Peptides

8 results for "Protein Arginine Methyltransferase Inhibitors Small Molecules and Peptides" in Products

8 results for "Protein Arginine Methyltransferase Inhibitors Small Molecules and Peptides" in Products

Protein Arginine Methyltransferase Inhibitors: Small Molecules and Peptides

Potent and selective PRMT 4 inhibitor

Chemical Name: N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide
Purity: ≥98% (HPLC)
Potent and selective PRMT 4 inhibitor

Potent and selective type I PRMT inhibitor

Chemical Name: N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine dihydrochloride
Purity: ≥98% (HPLC)
Potent and selective type I PRMT inhibitor

Potent and selective PRMT5 inhibitor

Chemical Name: N-[(2S)-3-(3,4-Dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide
Purity: ≥98% (HPLC)
Potent and selective PRMT5 inhibitor

Potent and selective allosteric inhibitor of PRMT3

Chemical Name: 1-(Isoquinolin-6-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl] urea
Purity: ≥98% (HPLC)
Potent and selective allosteric inhibitor of PRMT3

Potent and selective PRMT6 allosteric inhibitor

Chemical Name: (R)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
Purity: ≥98% (HPLC)
Potent and selective PRMT6 allosteric inhibitor

Negative control of SGC 707 (Cat. No. 5367)

Chemical Name: N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea
Purity: ≥98% (HPLC)
Negative control of SGC 707 (Cat. No. 5367)

Selective PRMT5 Degrader (PROTAC®)

Chemical Name: N-((S)-3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-((1-((S)-19-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidine-1-carbonyl)-20,20-dimethyl-17-oxo-3,6,9,12,15-pentaoxa-18-azahenicosanoyl)azetidin-3-yl)amino)pyrimidine-4-carboxamide
Purity: ≥98% (HPLC)
Selective PRMT5 Degrader (PROTAC®)

Negative control for SGC 6870 (Cat. No. 7182)

Chemical Name: (S)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
Purity: ≥98% (HPLC)
Negative control for SGC 6870 (Cat. No. 7182)
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