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P-Selectin/CD62P Products
P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex ) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produces a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.
27 results for "P-Selectin/CD62P" in Products
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P-Selectin/CD62P Products
P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex ) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produces a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.
27 results for "P-Selectin/CD62P" in Products
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
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ELISA
| Sensitivity : | 0.121 ng/mL |
| Assay Range : | 0.781 - 50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Applications : | ELISA |
BA
| Source : | NS0 |
| Accession # : | P16109 |
| Applications : | Bioactivity |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #BBIG-E6 (13D5) |
| Applications : | Flow Cytometry |
BA
| Source : | CHO |
| Accession # : | P16109 |
| Applications : | Bioactivity |
IHC, AdBlk
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #9E1 |
| Applications : | Block/Neutralize, Immunohistochemistry |
Catalog #:
11035-PS
BA
| Source : | HEK293 |
| Accession # : | NP_002996.2 |
| Applications : | Bioactivity |
WB, Simple Western, IHC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Simple Western, Western Blot |
Catalog #:
737-PS
BA
| Source : | NS0 |
| Accession # : | Q01102 |
| Applications : | Bioactivity |
ELISA
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
Flow, IP, AdBlk, CyTOF-ready, ICC
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #BBIG-E6 (13D5) |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation |
Selective inhibitor of P-selectin-mediated cell adhesion
| Chemical Name : | 3-[7-(2,4-Dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-2H-pyran-2-one |
| Purity : | ≥97% (HPLC) |
ELISA
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
Catalog #:
BBA32
WB, AdBlk
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Block/Neutralize, Western Blot |
ELISA
| Sensitivity : | 0.018 ng/mL |
| Assay Range : | 0.31 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
| Applications : | ELISA |
Catalog #:
MAB737
WB
| Clonality : | Monoclonal |
| Host : | Rat IgG2b Clone #127933 |
| Applications : | ELISA Capture, Western Blot |
Catalog #:
BAF137
WB
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
Catalog #:
BAF737
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
WB, Simple Western, AdBlk
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Block/Neutralize, Simple Western, Western Blot |
BA
| Source : | NS0 |
| Accession # : | Q01102 |
| Applications : | Bioactivity |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #BBIG-E6 (13D5) |
| Applications : | Flow Cytometry |
Catalog #:
FAB6169P
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #BBIG-E6 (13D5) |
| Applications : | Flow Cytometry |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #9E1 |
| Applications : | Flow Cytometry |
