MMP-14/MT1-MMP Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
166 results for "MMP-14/MT1-MMP" in Products
166 results for "MMP-14/MT1-MMP" in Products
MMP-14/MT1-MMP Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5H2 |
| Applications: | WB, IHC, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6T7L3 |
| Applications: | IHC, WB, ELISA, Flow |
![Western Blot: MMP-14/MT1-MMP Antibody (6T7L3) [NBP3-15247]](https://resources.bio-techne.com/images/products/MMP-14-MT1-MMP-Antibody-6T7L3-Western-Blot-NBP3-15247-img0001.jpg "Western Blot: MMP-14/MT1-MMP Antibody (6T7L3) [NBP3-15247]")
| Source: | E. coli |
| Accession #: | P50281 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #128527 |
| Applications: | WB, Flow, IHC, IP, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #3-F7 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Western Blot: MMP-14/MT1-MMP Antibody (3-F7) [NBP2-67415]](https://resources.bio-techne.com/images/products/MMP-14-MT1-MMP-Antibody-3-F7-Western-Blot-NBP2-67415-img0008.jpg "Western Blot: MMP-14/MT1-MMP Antibody (3-F7) [NBP2-67415]")
| Alternate Names: | BB-94 |
| Chemical Name: | (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | BB 2516,Marimistat |
| Chemical Name: | (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #128527 |
| Applications: | Flow |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Source: | NS0 |
| Accession #: | P50281 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #128527 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #128527 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #6A11D1 |
| Applications: | IHC, WB, ELISA, Flow, CyTOF-ready |
![Western Blot: MMP-14/MT1-MMP Antibody (6A11D1)BSA Free [NBP2-52512]](https://resources.bio-techne.com/images/products/MMP-14-MT1-MMP-Antibody-6A11D1-Western-Blot-NBP2-52512-img0004.jpg "Western Blot: MMP-14/MT1-MMP Antibody (6A11D1)BSA Free [NBP2-52512]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Chemical Name: | 3,4-Dichloro-N-(1-methylbutyl)benzamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #128527 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #128527 |
| Applications: | Flow |