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MMP-14/MT1-MMP Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
20 results for "MMP-14/MT1-MMP" in Products
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MMP-14/MT1-MMP Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
20 results for "MMP-14/MT1-MMP" in Products
| Source : | E. coli |
| Accession # : | P50281 |
| Applications : | Enzyme Activity |
Broad spectrum MMP inhibitor
| Alternate Names : | BB 2516, Marimistat |
| Chemical Name : | (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide |
| Purity : | ≥99% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
Histone deacetylase inhibitor
| Chemical Name : | 3,4-Dichloro-N-(1-methylbutyl)benzamide |
| Purity : | ≥99% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot |
Potent MMP inhibitor
| Alternate Names : | SC 78080 |
| Chemical Name : | N-Hydroxy-1-(2-methoxyethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl]-4-piperidinecarboxamide hydrochloride |
| Purity : | ≥98% (HPLC) |
Broad spectrum MMP inhibitor
| Chemical Name : | N-[(4'-Bromo[1,1'-biphenyl]-4-yl)sulfonyl]-L-valine |
| Purity : | ≥99% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #5H2 |
| Applications : | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | P50281 |
| Applications : | Enzyme Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
Potent, broad spectrum MMP inhibitor
| Alternate Names : | BB-94 |
| Chemical Name : | (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide |
| Purity : | ≥99% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #128527 |
| Applications : | Flow Cytometry |
