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MMP-14/MT1-MMP Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

20 results for "MMP-14/MT1-MMP" in Products

MMP-14/MT1-MMP Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

20 results for "MMP-14/MT1-MMP" in Products

EnzAct

Broad spectrum MMP inhibitor

Flow

Histone deacetylase inhibitor

WB, Flow, IHC, IP, CyTOF-ready

Potent MMP inhibitor

Broad spectrum MMP inhibitor

WB, IHC, IP
WB, Flow, IHC, CyTOF-ready
EnzAct

Potent, broad spectrum MMP inhibitor

Catalog #: FAB9181R
Flow
Catalog #: FAB9181U
Flow
Catalog #: FAB9181V
Flow
Catalog #: FAB9181T
Flow
Flow
Catalog #: FAB9181S
Flow
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