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8 results for "Immunosuppressants Small Molecules and Peptides" in Products

Immunosuppressants: Small Molecules and Peptides

Immunosuppressants are compounds that suppress the immune system and are used to treat inflammatory and autoimmune conditions such as asthma, rheumatoid arthritis and multiple sclerosis. They are also used for the prevention and treatment of organ transplant rejection.

mTOR inhibitor; immunosuppressant

Chemical Name: (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
Purity: ≥98% (HPLC)
mTOR inhibitor; immunosuppressant

Calcineurin inhibitor

Alternate Names: Ciclosporin A
Purity: ≥98% (HPLC)
Calcineurin inhibitor

Adrenal glucocorticoid; immunosuppressant

Chemical Name: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione
Purity: ≥98% (HPLC)
Adrenal glucocorticoid; immunosuppressant

Potent calcineurin inhibitor; immunosuppressant

Alternate Names: Tacrolimus,Fujimycin
Chemical Name: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone
Purity: ≥98% (HPLC)
Potent calcineurin inhibitor; immunosuppressant

Inosine monophosphatase dehydrogenase (IMPDH) inhibitor

Chemical Name: 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid
Purity: ≥98% (HPLC)
Inosine monophosphatase dehydrogenase (IMPDH) inhibitor

Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

Chemical Name: (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
Purity: ≥98% (HPLC)
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

Inosine monophosphate dehydrogenase (IMPDH) inhibitor

Chemical Name: 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester
Purity: ≥98% (HPLC)
Inosine monophosphate dehydrogenase (IMPDH) inhibitor

Inhibitor of DHODH; active metabolite of Leflunomide

Alternate Names: A77 1726
Chemical Name: 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
Purity: ≥98% (HPLC)
Inhibitor of DHODH; active metabolite of Leflunomide
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