9 results for "Histamine H3 R Small Molecules and Peptides" in Products
Histamine H3 R Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors Histamine H1 R, Histamine H2 R, Histamine H3 R and Histamine H4 R. HRH3 encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. Histamine H3 R is an integral membrane protein and can regulate neurotransmitter release. It can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
H3 antagonist; also H4 inverse agonist
Standard H3 and H4 agonist (H3 > H4)
Highly potent H3 antagonist and H4 partial agonist
Standard H3 agonist. Also H4 agonist
H1/ H2 agonist
Caged dopamine; photolysed by UV light
Potent and selective H3 inverse agonist
High affinity H3 antagonist
