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11 results for "Histamine H1 R Small Molecules and Peptides" in Products

Histamine H1 R: Small Molecules and Peptides

Histamine H1R (HRH1) is a G-protein coupled 7-transmembrane putative glycoprotein that is implicated in the pathogenesis of asthma and is a major pharmaceutical target for antihistamines. It has been detected as a mixture of monomers and homodimers, with highest concentration in the placenta, followed by brain, lung (produced by airway smooth muscle, bronchial epithelium and macrophages) and other tissues.

Endogenous histamine receptor agonist

Chemical Name: 2-(4-Imidazolyl)ethylamine dihydrochloride
Endogenous histamine receptor agonist

H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Chemical Name: α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Purity: ≥98% (HPLC)
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker

Alternate Names: Hismanal
Chemical Name: 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
Purity: ≥98% (HPLC)
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Alternate Names: Org 3770,6-Azamianserin
Chemical Name: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
Purity: ≥98% (HPLC)
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

H1 antagonist

Alternate Names: DPH
Chemical Name: 2-Diphenylmethoxy-N,N-dimethylethanamine hydrochloride
Purity: ≥98% (HPLC)
H1 antagonist

H1 antagonist

Chemical Name: (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy]ethyl]-1-methyl-2-pyrrolidine fumarate
Purity: ≥98% (HPLC)
H1 antagonist

H1 antagonist; ocular antiallergic agent

Chemical Name: (Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-acetic acid hydrochloride
Purity: ≥98% (HPLC)
H1 antagonist; ocular antiallergic agent

H1 agonist

Chemical Name: 2-Pyridineethanamine dihydrochloride
Purity: ≥99% (HPLC)
H1 agonist

H1/ H2 agonist

Alternate Names: Histamine trifluoromethyl toluidide
Chemical Name: 6-[2-(4-Imidazolyl)ethylamino]-N-(4-trifluoromethylphenyl)heptanecarboxamide dimaleate
Purity: ≥99% (HPLC)
H1/ H2 agonist

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98% (HPLC)
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Human pregnane X receptor agonist; H1 antagonist

Alternate Names: Meclozine
Chemical Name: 1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazine dihydrochloride
Purity: ≥99% (HPLC)
Human pregnane X receptor agonist; H1 antagonist
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