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Flt-3/Flk-2 Products
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.
50 results for "Flt-3/Flk-2" in Products
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Flt-3/Flk-2 Products
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.
50 results for "Flt-3/Flk-2" in Products
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Simple Western, Western Blot |
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
Potent VEGFR, PDGFRβ and KIT inhibitor
| Alternate Names : | SU 11248 |
| Chemical Name : | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Purity : | ≥99% (HPLC) |
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
| Chemical Name : | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity : | ≥98% (HPLC) |
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
| Alternate Names : | LDK378 |
| Chemical Name : | 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #113308 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Potent and selective PDGFR family inhibitor
| Chemical Name : | N-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-2-pyridinecarboxamide |
| Purity : | ≥99% (HPLC) |
| Assay Range : | 156 - 10,000 pg/mL |
| Applications : | ELISA |
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names : | Semaxinib |
| Chemical Name : | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity : | ≥99% (HPLC) |
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
| Alternate Names : | CEP-701 |
| Chemical Name : | (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
| Purity : | ≥99% (HPLC) |
Potent VEGFR inhibitor; also inhibits other RTKs
| Alternate Names : | Cabozantinib, BMS 907351 |
| Chemical Name : | N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Purity : | ≥98% (HPLC) |
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
| Chemical Name : | 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine |
| Purity : | ≥98% (HPLC) |
Potent FLT3 inhibitor
| Chemical Name : | 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide |
| Purity : | ≥99% (HPLC) |
Highly potent FLT3 inhibitor
| Chemical Name : | N-[5-(1,1-Dimethylethyl)-3-isoxazolyl]-N'-[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]urea |
| Purity : | ≥98% (HPLC) |
Potent VEGFR inhibitor; also aromatase inhibitor
| Alternate Names : | CGP 79787D, PTK787/ZK222584 |
| Chemical Name : | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate |
| Purity : | ≥99% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #113315 |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, ELISA, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #66903 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #66907 |
| Applications : | ELISA, Western Blot |
