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265 results for "FKBP12" in Products

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FKBP12 Products

FK506 binding protein, also called FKBP12 and FKBP1A, was originally characterized as a peptidyl-prolyl isomerase that catalyzes the transition between cis- and trans-proline residues critical for proper folding of proteins. The macrolide immunosuppressants FK506 (Tacrolimus) and rapamycin bind to FKBP12 with high affinity, while the structurally related-compound cyclosporine binds with a much lower affinity. The binding of these drugs causes FKBP12 to become a potent inhibitor of calcineurin phosphatase activity and TOR kinase activity. Knockout mice lacking FKBP12 are morphologically normal, but develop cardiomyopathies that may be related to dysregulation of ryanodyne receptors.

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor™ Plus 555-conjugated Antibody

Catalog #: FAB4174AFP555
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor™ Plus 488-conjugated Antibody

Catalog #: FAB4174AFP488
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor™ Plus 680-conjugated Antibody

Catalog #: FAB4174AFP680
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor™ Plus 647-conjugated Antibody

Catalog #: FAB4174AFP647
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor™ Plus 405-conjugated Antibody

Catalog #: FAB4174AFP405
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB4174V
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC

Human/Mouse/Rat FKBP12/FKBP12.6 Antibody

Catalog #: MAB4174
(1)
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC
Detection of Human, Mouse, and Rat FKBP12 and FKBP12.6 antibody by Western Blot.
(3)

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor™ Plus 594-conjugated Antibody

Catalog #: FAB4174AFP594
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB4174S
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB4174X
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB4174R
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB4174U
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB4174T
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB4174G
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC

Human/Mouse/Rat FKBP12/FKBP12.6 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB4174N
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #426227
Applications: WB, IHC

Human FKBP12 Alexa Fluor™ Plus 594-conjugated Antibody

Catalog #: FAB37771AFP594
Product Documents
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1049713

Human FKBP12 Antibody

Catalog #: MAB37771
Product Documents
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1049713
Applications: WB, ICC
(3)

Human FKBP12 Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB37771X
Product Documents
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1049713
Applications: WB, ICC

Human/Mouse/Rat FKBP12 Antibody

Catalog #: MAB3777
Citations (4)
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #422513
Applications: WB
Detection of Human/Mouse/Rat FKBP12 antibody by Western Blot.

Human/Mouse/Rat FKBP12 Alexa Fluor™ Plus 594-conjugated Antibody

Catalog #: FAB3777AFP594
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #422513

Human/Mouse/Rat FKBP12 Alexa Fluor™ Plus 647-conjugated Antibody

Catalog #: FAB3777AFP647
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #422513

Human/Mouse/Rat FKBP12 Alexa Fluor™ Plus 488-conjugated Antibody

Catalog #: FAB3777AFP488
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #422513

Rat FKBP12 ELISA Kit (Colorimetric)

Catalog #: NBP3-53306
Applications: ELISA

Human/Mouse/Rat FKBP12 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB3777S
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #422513
Applications: WB

Human/Mouse/Rat FKBP12 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB3777R
Product Documents
Reactivity: Human, Mouse, Rat
Details: Rat IgG2b Monoclonal Clone #422513
Applications: WB
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