COX-1: Small Molecules and Peptides
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
7 results for "COX-1 Small Molecules and Peptides" in Products
7 results for "COX-1 Small Molecules and Peptides" in Products
COX-1: Small Molecules and Peptides
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
Cyclooxygenase inhibitor (COX-1 > COX-2)
| Chemical Name: | 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase inhibitor; NSAID
| Chemical Name: | 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase inhibitor
| Chemical Name: | 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase inhibitor; may be selective for COX-3
| Alternate Names: | Paracetamol |
| Chemical Name: | N-(4-Hydroxyphenyl)acetamide |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase-1 (COX-1) inhibitor
| Chemical Name: | 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase inhibitor; NSAID
| Chemical Name: | 2-Acetoxybenzoic acid |
| Purity: | ≥98% (HPLC) |
Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6
| Chemical Name: | 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid |
| Purity: | ≥98% (HPLC) |
