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CD40/TNFRSF5 Products
CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.
57 results for "CD40/TNFRSF5" in Products
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CD40/TNFRSF5 Products
CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.
57 results for "CD40/TNFRSF5" in Products
Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
Catalog #:
ARY012
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Catalog #:
FCSTM24
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
WB, Simple Western, AgAct
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Functional Assay, Simple Western, Western Blot |
Flow, AgAct, CyTOF-ready, ICC
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #82111 |
| Applications : | CyTOF-ready, Flow Cytometry, Functional Assay, Immunocytochemistry/Immunofluorescence |
WB, Neut
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #82102 |
| Applications : | Block/Neutralize, Western Blot |
BA
| Source : | NS0 |
| Accession # : | P25942-1 |
| Applications : | Bioactivity |
Flow, IP, AgAct, CyTOF-ready
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #1C10 |
| Applications : | CyTOF-ready, Flow Cytometry, Functional Assay, Immunoprecipitation |
Catalog #:
MAB4401
WB, Flow, CyTOF-ready
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #65924 |
| Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry, Western Blot |
Catalog #:
AVI10380
BA
| Source : | CHO |
| Accession # : | P25942.1 |
| Applications : | Bioactivity |
WB, ICC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
Catalog #:
AFG1493
BA
Fc Chimera His-tag
| Source : | NS0 |
| Accession # : | P25942-1 |
| Applications : | Bioactivity |
Catalog #:
FAB6321A
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #82111 |
| Applications : | Flow Cytometry |
Catalog #:
SPCKB-PS-000196
Simple Plex Cartridge Kit containing CD40 for use with Human Plasma/Serum. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
ELISA
| Sensitivity : | 5.56 pg/mL |
| Assay Range : | 19.5 - 1,250 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine, Human Milk) |
| Applications : | ELISA |
ELISA
| Sensitivity : | 3.7 pg/mL |
| Assay Range : | 7.81 - 500 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Catalog #:
BAF440
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
Catalog #:
BAF632
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Catalog #:
BAM440
IP, ICC, IF
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #1C10 |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunoprecipitation |
Catalog #:
5602
CD40-TRAF6 interaction inhibitor
| Chemical Name : | 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one |
| Purity : | ≥99% (HPLC) |
Catalog #:
9660-CD
BA
| Source : | HEK293 |
| Accession # : | XP_005569274.1 |
| Applications : | Bioactivity |
