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CD40/TNFRSF5 Products

CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.

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408 results for "CD40/TNFRSF5" in Products

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CD40/TNFRSF5 Products

CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.

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408 results for "CD40/TNFRSF5" in Products

WB, Simple Western, AgAct

Simple Plex Human CD40/TNFRSF5 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Flow, AgAct, CyTOF-ready, ICC
Flow, IP, AgAct, CyTOF-ready
WB, Flow, CyTOF-ready
Catalog #: 898323
Ctrl

Control for use with Human CD40/TNFRSF5 Simple Plex Cartridge Kit

WB
Flow, Func, ICC/IF, IHC

Clone mAb89 was used by HLDA to establish CD designation.

Flow, Func, ICC/IF, IHC

Clone G28-5 was used by HLDA to establish CD designation.

BA
BA

Fc Chimera His-tag

BA

Fc Chimera His-tag

IHC, WB
ICC/IF, IHC, IP, WB

Recombinant Monoclonal Antibody.

IHC, WB
IP, ICC, IF
Flow
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