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CD40/TNFRSF5 Products

CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.

57 results for "CD40/TNFRSF5" in Products

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CD40/TNFRSF5 Products

CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.

57 results for "CD40/TNFRSF5" in Products

Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies

Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

WB, Simple Western, AgAct
Flow, AgAct, CyTOF-ready, ICC
Flow, IP, AgAct, CyTOF-ready
WB, Flow, CyTOF-ready
BA
BA

Fc Chimera His-tag

Flow
Catalog #: QC60
Ctrl

For use with catalog number DCCD40

Simple Plex Cartridge Kit containing CD40 for use with Human Plasma/Serum. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

WB
Catalog #: BAF632
WB
IP, ICC, IF

CD40-TRAF6 interaction inhibitor

BA
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