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CD40/TNFRSF5: Antibodies

CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.

33 results for "CD40/TNFRSF5 Primary Antibodies" in Products

CD40/TNFRSF5: Antibodies

CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.

33 results for "CD40/TNFRSF5 Primary Antibodies" in Products

Flow, AgAct, CyTOF-ready, ICC
WB, Simple Western, AgAct
WB
Flow, IP, AgAct, CyTOF-ready
Flow
WB, Flow, CyTOF-ready
Catalog #: BAF632
WB
IP, ICC, IF
Catalog #: FAB6321G
Flow
Catalog #: FAB6321T
Flow
Catalog #: FAB4401G
Flow
Catalog #: FAB4401N
Flow
Flow
Catalog #: FAB6321V
Flow
Catalog #: FAB6321U
Flow
Catalog #: FAB6321N
Flow
Catalog #: FAB6321R
Flow
Catalog #: FAB6321S
Flow
Catalog #: FAB4401U
Flow
Catalog #: FAB4401R
Flow
Catalog #: FAB4401S
Flow
Catalog #: FAB4401T
Flow
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