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CD40/TNFRSF5: Antibodies

CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.

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386 results for "CD40/TNFRSF5 Primary Antibodies" in Products

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CD40/TNFRSF5: Antibodies

CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.

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386 results for "CD40/TNFRSF5 Primary Antibodies" in Products

ELISA, Flow, Func

Recombinant Monoclonal Antibody

Flow, AgAct, CyTOF-ready, ICC
WB, Simple Western, AgAct
Flow, IP, AgAct, CyTOF-ready
WB, Flow, CyTOF-ready
IHC, ICC/IF, Flow, Func

Clone mAb89 was used by HLDA to establish CD designation.

WB
IHC, ICC/IF, Flow, Func

Clone G28-5 was used by HLDA to establish CD designation.

IHC, WB
IHC, WB, ICC/IF, IP

Recombinant Monoclonal Antibody.

IHC, WB
IP, ICC, IF
Flow
IHC, ICC/IF, Flow
Flow
Catalog #: BAF632
WB
IHC, ICC/IF, Flow

Clone 5C3 was used by HLDA to establish CD designation.

Catalog #: FAB6321R
Flow
Catalog #: FAB6321U
Flow
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