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327 results for "BTK" in Products

BTK Products

Bruton tyrosine kinase (Btk) is a 75 kDa cytoplasmic protein tyrosine kinase that is widely expressed in hematopoietic cells. Btk is required for B cell receptor signaling and B cell development. Defects in Btk result in X-linked agammaglobulinemia which is characterized by a severely decreased level of circulating antibodies. Like other Tec family kinases, Btk contains a Pleckstrin homology domain, a Tec homology domain, an SH3 domain, an SH2 domain, and a protein kinase domain. Association of ...

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Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, Flow, ICC/IF
Western Blot: BTK [p Tyr223] AntibodyBSA Free [NBP1-78295]
(3)
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #566928
Applications:
WB, ICC/IF, Simple Western
(6)
Reactivity:
Human, Primate
Details:
Mouse IgG1 Monoclonal Clone #7F12H4
Applications:
IHC, WB, ICC/IF
Western Blot: BTK Antibody (7F12H4)BSA Free [NB110-87047]
(4)
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 Monoclonal Clone #OTI3A2
Applications:
IHC, WB, Flow, ICC/IF
Western Blot: BTK Antibody (OTI3A2) [NBP2-02472]
(9)
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 Monoclonal Clone #OTI3A2
Applications:
IHC, WB, Flow, ICC/IF, CyTOF-ready
Western Blot: BTK Antibody (OTI3A2)Azide and BSA Free [NBP2-70291]
(9)
Reactivity:
Human, Primate
Details:
Mouse IgG1 Monoclonal Clone #7F12H4
Applications:
IHC, WB, ICC/IF
Western Blot: BTK Antibody (7F12H4)Azide and BSA Free [NBP2-80605]
(4)
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #797837
Applications:
WB, Simple Western
Detection of Human Phospho-BTK (Y551) antibody by Western Blot.
(3)
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF
Western Blot: BTK Antibody [NBP1-89207]
(7)
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #720101
Applications:
WB, ICC/IF
Detection of Human Phospho-BTK (Y223) antibody by Western Blot.
(2)
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA, ICC/IF
Western Blot: BTK AntibodyBSA Free [NBP1-76596]
(5)
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Western Blot: BTK Antibody [NBP1-89206]
(6)

Highly potent pan-Src/Bcr-Abl inhibitor

Alternate Names:
BMS-354825
Chemical Name:
N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
Purity:
≥98%
Highly potent pan-Src/Bcr-Abl inhibitor
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Western Blot: BTK [p Tyr223] Antibody [NBP3-12916]
(4)

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse
Details:
Rabbit IgG Monoclonal Clone #2J9O8
Applications:
IHC, WB, ICC/IF
Western Blot: BTK Antibody (2J9O8) [NBP3-15612]
(4)

Potent, selective BTK inhibitor

Chemical Name:
2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide
Purity:
≥98%
Potent, selective BTK inhibitor
Reactivity:
Human
Source:
Sf 21 (baculovirus)
Accession #:
Q06187.3
Applications:
Enzyme Activity
(2)

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #3005A
Applications:
WB

Potent and selective BTK inhibitor

Chemical Name:
1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one
Purity:
≥98%
Potent and selective BTK inhibitor

Potent and selective BTK Degrader (PROTAC®)

Chemical Name:
4-(1,1-Dimethylethyl)-N-[3-[6-[[4-[[4-[6-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]acetyl]amino]hexyl]-1-piperazinyl]carbonyl]phenyl]amino]-4,5-dihydro-4-methyl-5-oxo-2-pyrazinyl]-2-methylphenyl]benzamide
Purity:
≥98%
Potent and selective BTK Degrader (PROTAC®)
Reactivity:
Human
Applications:
AC
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #23GB4815
Applications:
WB, ICC/IF
BTK [p Tyr223] Antibody (23GB4815)
(2)
Reactivity:
Human
R&D Systems VersaClone cDNA Plasmids

Potent ITK inhibitor; also inhibits BTK

Chemical Name:
(R)-3-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(3-methyl-4-(1-methylethyl))benzamide
Purity:
≥95%
Potent ITK inhibitor; also inhibits BTK

Potent BTK inhibitor

Chemical Name:
1-Cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity:
≥98%
Potent BTK inhibitor

Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk

Chemical Name:
3-[[2-[3-(4-Morpholinylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenol dihydrochloride
Purity:
≥98%
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
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