BAFF/BLyS/TNFSF13B Products
BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.
53 results for "BAFF/BLyS/TNFSF13B" in Products
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BAFF/BLyS/TNFSF13B Products
BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.
53 results for "BAFF/BLyS/TNFSF13B" in Products
Sensitivity : | 6.44 pg/mL |
Assay Range : | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Analyzed by SEC-MALS
Source : | NS0 |
Accession # : | Q9WU72 |
Applications : | Bioactivity |
Sensitivity : | 7.8 pg/mL |
Assay Range : | 46.9 - 3,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Simple Plex Human BAFF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Source : | CHO |
Accession # : | Q9Y275 |
Applications : | Bioactivity |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
Assay Range : | 39.1 - 2,500 pg/mL |
Applications : | ELISA |
A New rh BAFF is Now Available! The new protein is competitively priced and has no tag!
Assay Range : | 62.5 - 4,000 pg/mL |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #121808 |
Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Western Blot |
Clone 137314 was used by HLDA to establish CD designation
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #137314 |
Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #148725 |
Applications : | Block/Neutralize |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #121808 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clone 137314 was used by HLDA to establish CD designation
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #137314 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #121808 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #137317 |
Applications : | Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #121834 |
Applications : | Immunocytochemistry/Immunofluorescence |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #121808 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #121808 |
Applications : | Flow Cytometry |
Clone 137314 was used by HLDA to establish CD designation
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #137314 |
Applications : | Flow Cytometry |
Clone 137314 was used by HLDA to establish CD designation
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #137314 |
Applications : | Flow Cytometry |