Skip to main content

BAFF/BLyS/TNFSF13B: Antibodies

BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.

Show More

181 results for "BAFF/BLyS/TNFSF13B Primary Antibodies" in Products

Back to Search Results
Apply

Search

BAFF/BLyS/TNFSF13B: Antibodies

BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.

Show More

181 results for "BAFF/BLyS/TNFSF13B Primary Antibodies" in Products

WB, IHC, Neut
WB, CyTOF-ready, ICFlow
IHC
WB, CyTOF-ready, ICFlow

Clone 137314 was used by HLDA to establish CD designation

ELISA, ICC/IF, IHC, WB
WB
ICC
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241R
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241N
ICFlow

Clone 137314 was used by HLDA to establish CD designation

ICFlow
Catalog #: IC1241S
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241V
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241U
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241T
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241G
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Flow, Func, IHC
Results Per Page
5 10 25 50
/ 8