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BAFF/BLyS/TNFSF13B: Antibodies

BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.

26 results for "BAFF/BLyS/TNFSF13B Primary Antibodies" in Products

BAFF/BLyS/TNFSF13B: Antibodies

BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.

26 results for "BAFF/BLyS/TNFSF13B Primary Antibodies" in Products

Catalog #: FAB1357R
ICFlow
ICC
WB, CyTOF-ready, ICFlow
WB, CyTOF-ready, ICFlow

Clone 137314 was used by HLDA to establish CD designation

WB
WB, IHC, Neut
Catalog #: IC1241G
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: FAB1357N
ICFlow
ICFlow
Catalog #: FAB1357S
ICFlow
ICFlow
Catalog #: FAB1357U
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241R
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241V
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: FAB1357V
ICFlow
Catalog #: IC1241T
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241N
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241U
ICFlow

Clone 137314 was used by HLDA to establish CD designation

Catalog #: IC1241S
ICFlow

Clone 137314 was used by HLDA to establish CD designation

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