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B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
47 results for "B7-1/CD80" in Products
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B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
47 results for "B7-1/CD80" in Products
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37711 |
| Applications : | Block/Neutralize, CyTOF-ready, Dual RNAscope ISH-IHC, ELISA Capture, Flow Cytometry, Immunohistochemistry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, CyTOF-ready, ELISA Capture, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Source : | NS0 |
| Accession # : | Q00609 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | P33681 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #111114 |
| Applications : | Immunohistochemistry |
(High Purity Dimer)
| Source : | NS0 |
| Accession # : | P33681-1 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37711 |
| Applications : | Flow Cytometry |
| Source : | CHO |
| Accession # : | P33681 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37711 |
| Applications : | Flow Cytometry |
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37721 |
| Applications : | ELISA Detection, Western Blot |
| Source : | NS0 |
| Accession # : | Q00609 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | P33681.1 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | P33681.1 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #210408 |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37711 |
| Applications : | Flow Cytometry |
