
B7-1/CD80: Proteins and Enzymes
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
14 results for "B7-1/CD80 Proteins and Enzymes" in Products
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B7-1/CD80: Proteins and Enzymes
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
14 results for "B7-1/CD80 Proteins and Enzymes" in Products
Source : | HEK293 |
Accession # : | P33681.1 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | P33681 |
Applications : | Bioactivity |
(High Purity Dimer)
Source : | NS0 |
Accession # : | P33681-1 |
Applications : | Bioactivity |
Source : | NS0 |
Accession # : | Q00609 |
Applications : | Bioactivity |
Source : | CHO |
Accession # : | P33681 |
Applications : | Bioactivity |
Source : | NS0 |
Accession # : | Q00609 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | XP_005548122 |
Applications : | Bioactivity |
Source : | NS0 |
Accession # : | AAB60503 |
Applications : | Bioactivity |
Fc Chimera
Source : | HEK293 |
Accession # : | XP_005548122 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | P33681.1 |
Applications : | Bioactivity |