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Axl Products

Axl, also known as Ufo and Ark, is a widely expressed glycoprotein in the TAM receptor tyrosine kinase family. TAM family receptors (Dtk/Tyro3, Axl, and Mer) are involved in regulation of the inflammatory response, cell survival and migration, and tumorigenesis. Axl binds the vitamin K-dependent protein Gas6, triggering platelet aggregation and thrombus formation, macrophage and dendritic cell phagocytosis of apoptotic cells, NK cell development from hematopoietic progenitor cells, and in vivo angiogenesis. Axl is highly expressed in solid cancers and promotes in vivo tumorigenesis and tumor cell invasiveness. It contributes to vascular remodeling and inflammatory cell infiltration in response to hypertension and restricted blood flow. It also functions as a cellular entry receptor for Gas6-opsonized lentiviruses.

209 results for "Axl" in Products

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Axl Products

Axl, also known as Ufo and Ark, is a widely expressed glycoprotein in the TAM receptor tyrosine kinase family. TAM family receptors (Dtk/Tyro3, Axl, and Mer) are involved in regulation of the inflammatory response, cell survival and migration, and tumorigenesis. Axl binds the vitamin K-dependent protein Gas6, triggering platelet aggregation and thrombus formation, macrophage and dendritic cell phagocytosis of apoptotic cells, NK cell development from hematopoietic progenitor cells, and in vivo angiogenesis. Axl is highly expressed in solid cancers and promotes in vivo tumorigenesis and tumor cell invasiveness. It contributes to vascular remodeling and inflammatory cell infiltration in response to hypertension and restricted blood flow. It also functions as a cellular entry receptor for Gas6-opsonized lentiviruses.

209 results for "Axl" in Products

WB, Simple Western, Flow, IHC, Block, CyTOF-ready, KO
Flow, CyTOF-ready
Flow, CyTOF-ready, KO

Simple Plex Human Axl assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Catalog #: 898318
Ctrl

Control for use with Human Axl Simple Plex Cartridge Kit

WB, Simple Western, CyTOF-ready, ICC, ICFlow
ELISA
WB, Flow
Catalog #: FAB154RU
Flow

Recombinant Monoclonal Antibody

WB
Flow, KO
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