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Axl Products
Axl, also known as Ufo and Ark, is a widely expressed glycoprotein in the TAM receptor tyrosine kinase family. TAM family receptors (Dtk/Tyro3, Axl, and Mer) are involved in regulation of the inflammatory response, cell survival and migration, and tumorigenesis. Axl binds the vitamin K-dependent protein Gas6, triggering platelet aggregation and thrombus formation, macrophage and dendritic cell phagocytosis of apoptotic cells, NK cell development from hematopoietic progenitor cells, and in vivo angiogenesis. Axl is highly expressed in solid cancers and promotes in vivo tumorigenesis and tumor cell invasiveness. It contributes to vascular remodeling and inflammatory cell infiltration in response to hypertension and restricted blood flow. It also functions as a cellular entry receptor for Gas6-opsonized lentiviruses.
68 results for "Axl" in Products
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Axl Products
Axl, also known as Ufo and Ark, is a widely expressed glycoprotein in the TAM receptor tyrosine kinase family. TAM family receptors (Dtk/Tyro3, Axl, and Mer) are involved in regulation of the inflammatory response, cell survival and migration, and tumorigenesis. Axl binds the vitamin K-dependent protein Gas6, triggering platelet aggregation and thrombus formation, macrophage and dendritic cell phagocytosis of apoptotic cells, NK cell development from hematopoietic progenitor cells, and in vivo angiogenesis. Axl is highly expressed in solid cancers and promotes in vivo tumorigenesis and tumor cell invasiveness. It contributes to vascular remodeling and inflammatory cell infiltration in response to hypertension and restricted blood flow. It also functions as a cellular entry receptor for Gas6-opsonized lentiviruses.
68 results for "Axl" in Products
ELISA
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
Flow, CyTOF-ready, KO
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #108724 |
| Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry, Knockout Validated |
WB, IHC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
WB, IHC, ICC
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot |
WB, Simple Western, Flow, IHC, Block, CyTOF-ready, KO
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry, Knockout Validated, Simple Western, Western Blot |
Catalog #:
SPCKB-PS-000472
Simple Plex Cartridge Kit for quantitation of Axl. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Catalog #:
DAXL00
ELISA
| Sensitivity : | 4.6 pg/mL |
| Assay Range : | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine, Cerebrospinal Fluid) |
| Applications : | ELISA |
Catalog #:
10884-AX
BA
| Source : | CHO |
| Accession # : | EHH59605.1 |
| Applications : | Bioactivity |
Catalog #:
FAB154RR
Flow
Recombinant Monoclonal Antibody
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #108724R |
| Applications : | Flow Cytometry |
Catalog #:
FAB8541R
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #175128 |
| Applications : | Flow Cytometry |
Catalog #:
FAB154S
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #108724 |
| Applications : | Flow Cytometry |
Catalog #:
FAB154N
Flow, KO
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #108724 |
| Applications : | Flow Cytometry, Knockout Validated |
Flow
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #175128 |
| Applications : | Flow Cytometry |
ELISA
| Applications : | ELISA |
ELISA
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
Potent VEGFR inhibitor; also inhibits other RTKs
| Alternate Names : | Cabozantinib, BMS 907351 |
| Chemical Name : | N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Purity : | ≥98% (HPLC) |
ELISA
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
WB
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #107332 |
| Applications : | ELISA Capture, Western Blot |
WB, Flow
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Flow Cytometry, Western Blot |
Catalog #:
BAF854
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
