9 results for "Akt1" in Products
Akt1 Products
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
Potent MSK1 inhibitor; also inhibits other AGC group kinases
Akt kinase inhibitor. Antitumor
Selective Akt/PKB inhibitor
PKB/Akt inhibitor; also modulates Kv2.1 current
Potent and selective dual Akt1 and 2 inhibitor
Potent pan-AKT inhibitor
Potent pan-Akt and PKA inhibitor
Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor