API-2

Citations are publications that use Bio-Techne products. Selected citations for API-2 include:

• Yuan et al. (2019) IFT80 is required for stem cell proliferation, differentiation, and odontoblast polarization during tooth development. Cell Death Dis. 10:63
  PMID: 30683845
• Ali et al. (2017) Isolation and characterization of a new naturally immortalized human breast carcinoma cell line, KAIMRC1. BMC Cancer. 17:803
  PMID: 29187162
• Suarez et al. (2017) The AKT inhibitor triciribine in combination with PTX has order-specific efficacy against Zfp217-induced breast cancer chemoresistance. Oncotarget. 8:108534
  PMID: 29312549
• Arqués et al. (2016) Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer. Clin Cancer Res. 22:644
  PMID: 26224873
• Kana et al. (2015) PI3K Phosphorylation Is Linked to Improved Electrical Excitability in an In Vitro Engineered Heart Tissue Disease Model System. Tissue Eng Part A. 21:2379
  PMID: 26120935
• Rosenberg et al. (2015) Targeting Glutamatergic Signaling and the PI3 Kinase Pathway to Halt Melanoma Progression. Biol Open. 8:42614
  PMID: 25749171
• Shravah et al. (2014) PropF. mediates signal transducer and activator of transcription 3 activation and crosstalk with phosphoinositide 3-kinase/AKT. Am J Physiol Renal Physiol. 3:e29554
  PMID: 25105067
• Kuo et al. (2014) Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by Ins. J Lipid Res. 55:919
  PMID: 24565756
• Robertson et al. (2013) Sea urchin akt activity is Runx-dependent and required for post-cleavage stage cell division. Blood. 2:472
  PMID: 23789095
• Woo et al. (2012) Calpain-mediated processing of p53-associated parkin-like cytoplasmic protein (PARC) affects chemosensitivity of human ovarian cancer cells by promoting p53 subcellular trafficking. J Biol Chem. 287:3963
  PMID: 22117079
• Barber and Sentman (2011) NKG2D receptor regulates human effector T-cell cytokine production. Mol Cell. 117:6571
  PMID: 21518928
• Duan et al. (2011) mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR. JAKSTAT. 44:317
  PMID: 22017877
• Sunters et al. (2010) Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of Ins-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-i J Biol Chem. 285:8743
  PMID: 20042609
• Liu et al. (2010) FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-{kappa}B-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoE-knockout mouse model. Am J Physiol Endocrinol Metab. 299:E351
  PMID: 20530739
• Jackson et al. (2010) Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase. PLoS One. 5:e11962
  PMID: 20694145
• Roselli et al. (2009) Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways. PLoS One. 4:e6011
  PMID: 19547699
• Madhunapantula et al. (2007) PRAS40 deregulates apoptosis in malignant melanoma. Cancer Res. 67:3626
  PMID: 17440074

There are no citations that match your criteria.

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• Attenuation by co-treatment of either PI3K inhibitor LY94002 or Akt inhibitor API-2

  Name: Zhenmin Lei
  Species: Mouse
  Assay Type: In Vitro
  Cell Line/Tissue: Ovarian theca cells
  The isolated mouse ovarian theca cells were maintained in 12-well plates withRPMI-1640 medium. For determination of Lhcgr expression, thecells were rinsed three times with PBS the day before incubation with vehicle(DMSO), 740YP (50 mg/ml), 740YP + API-2 (7.5 mM), LH (50 ng/mL),or LH + API-2 for 24 h. For determination of Akt phosphorylation,PBS rinsed cells were incubated with vehicle (DMSO), or API-2 (7.5 mM) in serum-free RPMI-medium for 1 h before the addition of LH (50 ng/mL) for 30 min.
  PMID: PMID: 28137614
  

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