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Akt (Protein Kinase B) Inhibitors Products

Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.

12 results for "Akt (Protein Kinase B) Inhibitors" in Products

Akt (Protein Kinase B) Inhibitors Products

Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.

12 results for "Akt (Protein Kinase B) Inhibitors" in Products

PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro

Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates

Potent and selective dual Akt1 and 2 inhibitor

Potent pan-AKT inhibitor

Selective Akt/PKB inhibitor. Antitumor

Akt/PKB inhibitor

Potent pan-Akt and PKA inhibitor

Selective Akt/PKB inhibitor

Dual Akt and PDK1 inhibitor; antitumor

PKB/Akt inhibitor; also modulates Kv2.1 current

Akt kinase inhibitor. Antitumor

Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral

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