
Akt (Protein Kinase B) Inhibitors Products
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
12 results for "Akt (Protein Kinase B) Inhibitors" in Products
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Akt (Protein Kinase B) Inhibitors Products
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
12 results for "Akt (Protein Kinase B) Inhibitors" in Products
Akt/PKB inhibitor
Chemical Name : | Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex |
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
Chemical Name : | 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one |
Purity : | ≥98% (HPLC) |
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
Chemical Name : | 6-(2-Benzothiazolyl)-1-ethyl-2-[(1E)-2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide |
Purity : | ≥98% (HPLC) |
Potent and selective dual Akt1 and 2 inhibitor
Alternate Names : | Akt Inhibitor VIII |
Chemical Name : | 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
Purity : | ≥98% (HPLC) |
Selective Akt/PKB inhibitor
Alternate Names : | Akt Inhibitor X |
Chemical Name : | 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride |
Purity : | ≥99% (HPLC) |
Potent pan-AKT inhibitor
Alternate Names : | Capivasertib |
Chemical Name : | 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxamide |
Purity : | ≥98% (HPLC) |
Potent pan-Akt and PKA inhibitor
Chemical Name : | 4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine hydrochloride |
Purity : | ≥98% (HPLC) |
PKB/Akt inhibitor; also modulates Kv2.1 current
Alternate Names : | KRX-0401 |
Chemical Name : | Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate |
Purity : | ≥99% (HPLC) |
Dual Akt and PDK1 inhibitor; antitumor
Chemical Name : | 4-Dodecyl-N-1,3,4-thiadiazol-2-yl-benzenesulfonamide |
Purity : | ≥98% (HPLC) |
Selective Akt/PKB inhibitor. Antitumor
Chemical Name : | 4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide |
Purity : | ≥96% (HPLC) |
Akt kinase inhibitor. Antitumor
Chemical Name : | 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol |
Purity : | ≥98% (HPLC) |
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
Alternate Names : | Triciribine, NSC 154020, TCN |
Chemical Name : | 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine |
Purity : | ≥99% (HPLC) |