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Akt (Protein Kinase B) Inhibitors Products
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
12 results for "Akt (Protein Kinase B) Inhibitors" in Products
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Akt (Protein Kinase B) Inhibitors Products
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
12 results for "Akt (Protein Kinase B) Inhibitors" in Products
Akt/PKB inhibitor
| Chemical Name : | Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex |
Catalog #:
6762
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
| Chemical Name : | 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one |
| Purity : | ≥98% (HPLC) |
Catalog #:
5985
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
| Chemical Name : | 6-(2-Benzothiazolyl)-1-ethyl-2-[(1E)-2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide |
| Purity : | ≥98% (HPLC) |
Potent and selective dual Akt1 and 2 inhibitor
| Alternate Names : | Akt Inhibitor VIII |
| Chemical Name : | 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Purity : | ≥98% (HPLC) |
Selective Akt/PKB inhibitor
| Alternate Names : | Akt Inhibitor X |
| Chemical Name : | 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride |
| Purity : | ≥99% (HPLC) |
Catalog #:
6978
Potent pan-AKT inhibitor
| Alternate Names : | Capivasertib |
| Chemical Name : | 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxamide |
| Purity : | ≥98% (HPLC) |
Catalog #:
7001
Potent pan-Akt and PKA inhibitor
| Chemical Name : | 4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine hydrochloride |
| Purity : | ≥98% (HPLC) |
Catalog #:
6087
PKB/Akt inhibitor; also modulates Kv2.1 current
| Alternate Names : | KRX-0401 |
| Chemical Name : | Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate |
| Purity : | ≥99% (HPLC) |
Catalog #:
4598
Dual Akt and PDK1 inhibitor; antitumor
| Chemical Name : | 4-Dodecyl-N-1,3,4-thiadiazol-2-yl-benzenesulfonamide |
| Purity : | ≥98% (HPLC) |
Selective Akt/PKB inhibitor. Antitumor
| Chemical Name : | 4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide |
| Purity : | ≥96% (HPLC) |
Akt kinase inhibitor. Antitumor
| Chemical Name : | 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol |
| Purity : | ≥98% (HPLC) |
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
| Alternate Names : | Triciribine, NSC 154020, TCN |
| Chemical Name : | 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine |
| Purity : | ≥99% (HPLC) |
